Long-chain fatty acids are molecules that act as metabolic intermediates and constituents of
membranes; however, their novel role as signaling molecules in immune function has also …

The human diet contains low amounts of ω-3 polyunsaturated fatty acids (PUFAs) and high
amounts of ω-6 PUFAs, which has been reported to contribute to the incidence of cancer …

Doxorubicin (DOX) is widely used in cancer treatment, however, its use is often limited due
to its side effects. To avoid these shortcomings, the encapsulation of DOX into nanocarriers …

Many studies demonstrate that conventional anticancer drugs elevate intracellular level of
reactive oxygen species (ROS) and alter redox-homeostasis of cancer cells. It is widely …

The present study demonstrates specific sensitization of leukemia lymphocytes towards
anticancer drugs using melatonin and clarifies the role of reactive oxygen species (ROS) for …

Several phytochemicals, which display antioxidant activity and inhibit cancer cell
phenotypes, could be used for cancer treatment and prevention. Lignin, as a part of plant …

Background/Aim: The study is directed to the effect of resveratrol on the redox-status and
viability of leukemic and normal lymphocytes, as well as its ability to sensitize leukemic …

Purpose Most chemotherapeutic agents possess poor water solubility and show more
significant accumulations in normal tissues than in tumor tissues, resulting in serious side …

We previously reported a synergistic anticancer action of clioquinol and docosahexaenoic
acid (DHA) in human cancer cells. However, clioquinol has been banned from the clinic due …

We analyzed the role of ABCG2, a drug transporter, in determining the sensitivity of glioma
stem cells (GSCs) to demethoxycurcumin (DMC). We first demonstrated that ABCG2 is more …