Barbituric acid has been utilized in the design and synthesis of diverse types of heterocyclic
and carbocyclic compounds and considered as an important building block in organic …

Carbonic anhydrase inhibitors (CAIs) are of growing interest since various isoforms of the
enzyme are identified as promising drug targets for treatment of disease. The principal …

Heterocyclic compounds represent a prominent class of molecules with diverse
pharmacological activities. Among their therapeutic applications, they have gained …

The present study evaluated the phosphorylated-tyrosine (P-Tyr) based pseudobioaffinity
adsorbent for the purification of human immunoglobulin G (IgG). P-Tyr was selected as a …

New spiroindoline-substituted sulphonamide compounds were synthesised and their
inhibitory effects on the activity of purified human carbonic anhydrase I and II were …

Bu çalışmada, ilaç etken maddeleri olarak kullanılma potansiyeline sahip olabilecekleri
düşünülerek sentezlenmiş ve insan karbonik anhidraz I, II izoenzimlerini inhibe ettikleri …

Barbituric acid is an organic compound containing a pyrimidine heterocyclic skeleton. It is a
water-soluble and odorless compound. Barbituric acid served as a starting material for many …

In the present study, it was aimed to assess the genotoxic potentials of [4, 4-Dimethyl-2, 6-
dioxocyclohexylidene) methylamino) benzenesulfonamide](2b) and [4-((1, 3-Dimethyl-2, 4, 6 …

Enzimler sık kullanılan ilaç hedefleridir. Karbonik anhidraz enzimleri (KA) sık kullanılan ilaç
hedeflerinden biridir. Karbonik anhidrazlar CO2'nin hidrasyonu veya bikarbonatın …

Dihydro [2, 3D] pyridine substituted enaminosulfonamide compounds have been
synthesized and their effects on carbonic anhydrase II (hCAII) have been evaluated. Pyrido …