Critical features of human addiction are increasingly being incorporated into complementary
animal models, including escalation of drug intake, punished drug seeking and taking …

Purpose In routine practice, dopamine transporter (DAT) imaging is frequently used as a
diagnostic tool to support the diagnosis of Parkinson's disease or dementia with Lewy …

Background: cocaine craving is a core feature of cocaine use disorder and remains a critical
challenge for abstinence and relapse prevention. This review summarizes the anti-craving …

The present review focuses on potential neural mechanisms underlying recovery from
psychiatric conditions characterised by impaired impulse control, specifically substance use …

Modafinil (MOD) is a wakefulness-inducing compound prescribed for treatment of excessive
daytime sleepiness as a consequence of sleep disturbances such as shift work sleep …

Cocaine use disorder is a persistent public health problem for which no widely effective
medications exist. Self-administration procedures, which have shown good predictive …

Dopamine function and reward processing are highly interrelated and involve common brain
regions afferent to the nucleus accumbens, within the mesolimbic pathway. Although …

Alcohol and substance use disorders are heterogeneous conditions with limited effective
treatment options. While there have been prior attempts to classify addiction subtypes, they …

The current literature does not strongly support any individual MAT for CUD. Psychosocial
interventions, namely contingency management, have the most evidence for treatment of …

Neuroimaging techniques to measure the function and biochemistry of the human brain
such as positron emission tomography (PET), proton magnetic resonance spectroscopy (1 H …