Harnessing the potential of CD40 agonism in cancer therapy
Y Zhou, A Richmond, C Yan - Cytokine & Growth Factor Reviews, 2023 - Elsevier
CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily of receptors
expressed on a variety of cell types. The CD40–CD40L interaction gives rise to many …
expressed on a variety of cell types. The CD40–CD40L interaction gives rise to many …
Leishmania donovani impedes antileishmanial immunity by suppressing dendritic cells via the TIM-3 receptor
An immunological hallmark of visceral leishmaniasis (VL), caused by Leishmania donovani,
is profound immunosuppression. However, the molecular basis for this immune dysfunction …
is profound immunosuppression. However, the molecular basis for this immune dysfunction …
TIM-3 increases the abundance of type-2 dendritic cells during Leishmania donovani infection by enhancing IL-10 production via STAT3
The outcome of the disease visceral leishmaniasis (VL), caused by Leishmania donovani
(LD), largely relies on the relative dominance of host-protective type-1 T helper (Th1) cell …
(LD), largely relies on the relative dominance of host-protective type-1 T helper (Th1) cell …
Leishmania donovani attenuates dendritic cell trafficking to lymph nodes by inhibiting C-type lectin Receptor 2 expression via transforming growth factor-β
To initiate an antileishmanial adaptive immune response, dendritic cells (DCs) must carry
Leishmania antigens from peripheral tissues to local draining lymph nodes. However, the …
Leishmania antigens from peripheral tissues to local draining lymph nodes. However, the …
[HTML][HTML] The analysis of tumor-infiltrating immune cell and ceRNA networks in laryngeal squamous cell carcinoma
D Li, K Dong, J Su, H Xue, J Tian, Y Wu, J Wang - Medicine, 2022 - journals.lww.com
Background: Laryngeal squamous cell carcinoma (LSCC) is one of the most common forms
of head and neck cancers. However, few studies have focused on the correlation between …
of head and neck cancers. However, few studies have focused on the correlation between …