Autophagy-dependent cell death can be defined as cell demise that has a strict requirement
of autophagy. Although autophagy often accompanies cell death following many toxic …

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

Autophagy influences cell survival through maintenance of cell bioenergetics and clearance
of protein aggregates and damaged organelles. Several lines of evidence indicate that …

Endoplasmic reticulum (ER) stress is a common cellular stress response that is triggered by
a variety of conditions that disturb cellular homeostasis, and induces cell apoptosis …

Autophagy and apoptosis control the turnover of organelles and proteins within cells, and of
cells within organisms, respectively, and many stress pathways sequentially elicit …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Autophagy as a means of cell killing was first advanced by Clark's phenotypic description of
'Type II autophagic cell death'in 1990. However, this phenomenon later came into question …

Abstract In 2009, the Nomenclature Committee on Cell Death (NCCD) proposed a set of
recommendations for the definition of distinct cell death morphologies and for the …

Metastasis is a crucial hallmark of cancer progression, which involves numerous factors
including the degradation of the extracellular matrix (ECM), the epithelial-to-mesenchymal …

The ATP-dependent proton pump V-ATPase ensures low intralysosomal pH, which is
essential for lysosomal hydrolase activity. Based on studies with the V-ATPase inhibitor …