The pool of abundant chiral terpene building blocks (ie,“chiral pool terpenes”) has long
served as a starting point for the chemical synthesis of complex natural products, including …

Sesquiterpene lactones (STLs) are one of the largest biogenetically homogenous groups of
natural products known. Currently, the Dictionary of Natural Products holds a total of over …

As one of the largest groups of secondary plant metabolites, sesquiterpene lactones (STL)
possess a broad variety of conspicuous biological activities directed towards all types of …

The Illicium sesquiterpenes are a family of natural products containing over 100 highly
oxidized and structurally complex members, many of which display interesting biological …

Throughout the history of organic chemistry, we find that the study of natural products
frequently has provided the impetus for great advances. This is certainly true in total …

Hydrogenation and dehydrogenation reactions play a key role in synthetic organic
chemistry. The discoveries that selenium and sulfur substituents could be easily introduced …

Illicium sesquiterpenes have been the subject of numerous synthetic efforts due to their
ornate and highly oxidized structures as well as significant biological activities. Herein we …

We report the first chemical syntheses of both (−)-majucin and (−)-jiadifenoxolane A via 10
net oxidations from the ubiquitous terpene (+)-cedrol. Additionally, this approach allows for …

The first total synthesis of jiadifenolide (1), a potent neurotrophic modulator, has been
reported. Highlights of the synthesis include: construction of the B ring via an asymmetric …

A convulsant natural product known as anisatin was isolatedl over forty years ago from the
Japanese star anise Illicium anisatum, yet it was not until 1965 that it was characterized2 as …