Ectopic odorant receptor responding to flavor compounds: Versatile roles in health and disease

T Tong, Y Wang, SG Kang, K Huang - Pharmaceutics, 2021 - mdpi.com
Prompted by the ground-breaking discovery of the rodent odorant receptor (OR) gene family
within the olfactory epithelium nearly 30 years ago, followed by that of OR genes in cells of …

Combinative ex vivo studies and in silico models ProTox-II for investigating the toxicity of chemicals used mainly in cosmetic products

P Banerjee, OC Ulker - Toxicology mechanisms and methods, 2022 - Taylor & Francis
Human data on remains sparse and of varying quality and reproducibility. Ex vivo
experiments and animal experiments currently is the most preferred way to predict the skin …

Allergic potential & molecular mechanism of skin sensitization of cinnamaldehyde under environmental UVB exposure

SK Patel, A Vikram, D Pathania, R Chugh, P Gaur… - Chemosphere, 2024 - Elsevier
Fragrance, a key ingredient in cosmetics, often triggers skin allergy causes rashes, itching,
dryness, and cracked or scaly skin. Cinnamaldehyde (CA), derived from the bark of the …

[HTML][HTML] Use of alternative test methods in a tiered testing approach to address photoirritation potential of fragrance materials

G Ritacco, A Hilberer, M Lavelle, AM Api - Regulatory Toxicology and …, 2022 - Elsevier
The safety assessment of fragrance materials for photoirritation utilized by The Research
Institute for Fragrance Materials has recently been modified and is described in detail …

Identification of anti-SARS-CoV-2 agents based on flavor/fragrance compositions that inhibit the interaction between the virus receptor binding domain and human …

Y Nishimura, K Nomiyama, S Okamoto, M Igarashi… - Plos one, 2022 - journals.plos.org
Coronavirus disease 2019 (COVID-19) pandemic poses a threat to human beings and
numerous cases of infection as well as millions of victims have been reported. The binding …

Contact allergy to fragrance mix I and its components in individuals with photocontact allergy to ketoprofen

V Marmgren, M Mowitz, E Zimerson… - Contact …, 2021 - Wiley Online Library
Background Contact allergy to fragrance mix I (FM I) is over‐represented in patients
photoallergic to ketoprofen. The prevalence of contact allergy to two components of FM I …

In Silico Phototoxicity Prediction of Drugs and Chemicals by using Derek Nexus and QSAR Toolbox

V Ahuja, G Adiga Perdur, Z Aj… - Alternatives to …, 2024 - journals.sagepub.com
Phototoxicity testing is crucial for evaluating the potential harmful effects of pharmaceuticals
and chemicals on human skin when exposed to sunlight. Traditional in vivo models …

Fragrances in the Environment: Properties, Applications, and Emissions

F Rocha, N Ratola, V Homem - 2023 - Springer
Olfactory stimuli are processed in the human brain in a complex integrative system with
other senses, and intimately wired to cortical areas related to the formation of memories …

Photocontact Allergy to Ketoprofen and Simultaneous Contact Allergies

V Marmgren - 2021 - portal.research.lu.se
Ketoprofen is a non-steroidal anti-inflammatory drug with analgesic, antipyretic, and anti-
inflammatory properties. It is available in both oral and topical formulations. Photocontact …

Toxicology of Flavoring Ingredients in the Food Industry

AM Pecquet, C Bates, MA Maier - Patty's Toxicology, 2001 - Wiley Online Library
The present chapter represents toxicological information on selected flavoring ingredients
commonly found in the food and beverage product manufacturing workplace. Many flavoring …