Modern theories of memory storage have largely focused on persistent, experience-
dependent changes in synaptic function such as long-term potentiation and depression. But …

The aldo-keto reductase (AKR) superfamily comprises enzymes that catalyze redox
transformations involved in biosynthesis, intermediary metabolism, and detoxification …

▪ Abstract The intrinsic electrical properties of neurons are shaped in large part by the action
of voltage-gated ion channels. Molecular cloning studies have revealed a large family of ion …

Most molecular and cellular studies of cognitive function have focused on either normal or
pathological states, but recent research with transgenic mice has started to address the …

Since the first discovery of Kvβ-subunits more than 15 years ago, many more ancillary Kv
channel subunits were characterized, for example, KChIPs, KCNEs, and BKβ-subunits. The …

The role of large-conductance Ca 2+-dependent K+ channels (BK-channels; also known as
maxi-K-or slo-channels) in spike broadening during repetitive firing was studied in CA1 …

KChIP2, a gene encoding three auxiliary subunits of Kv4. 2 and Kv4. 3, is preferentially
expressed in the adult heart, and its expression is downregulated in cardiac hypertrophy …

Neocortical layer 1 (L1) is a site of convergence between pyramidal-neuron dendrites and
feedback axons where local inhibitory signaling can profoundly shape cortical processing …

Currently, no treatment can prevent the cognitive and motor decline associated with
widespread neurodegeneration in prion disease. However, we previously showed that …

Rapidly activating and inactivating cardiac transient outward K+ currents, Ito, are expressed
in most mammalian cardiomyocytes, and contribute importantly to the early phase of action …