Perlecan, a multi-functional, cell-instructive, matrix-stabilizing proteoglycan with roles in tissue development has relevance to connective tissue repair and …
This review highlights the multifunctional properties of perlecan (HSPG2) and its potential
roles in repair biology. Perlecan is ubiquitous, occurring in vascular, cartilaginous, adipose …
roles in repair biology. Perlecan is ubiquitous, occurring in vascular, cartilaginous, adipose …
Biomaterials containing extracellular matrix molecules as biomimetic next-generation vascular grafts
The performance of synthetic biomaterial vascular grafts for the bypass of stenotic and
dysfunctional blood vessels remains an intractable challenge in small-diameter applications …
dysfunctional blood vessels remains an intractable challenge in small-diameter applications …
Surface biofunctionalization of silk biomaterials using dityrosine cross-linking
Biofunctionalization of silk biomaterial surfaces with extracellular matrix (ECM) molecules,
cell binding peptides, or growth factors is important in a range of applications, including …
cell binding peptides, or growth factors is important in a range of applications, including …
Diverse and multifunctional roles for perlecan (HSPG2) in repair of the intervertebral disc
Perlecan is a widely distributed, modular, and multifunctional heparan sulfate proteoglycan,
which facilitates cellular communication with the extracellular environment to promote tissue …
which facilitates cellular communication with the extracellular environment to promote tissue …
Tuning Recombinant Perlecan Domain V to Regulate Angiogenic Growth Factors and Enhance Endothelialisation of Electrospun Silk Vascular Grafts
Synthetic vascular grafts are used to bypass significant arterial blockage when native blood
vessels are unsuitable, yet their propensity to fail due to poor blood compatibility and …
vessels are unsuitable, yet their propensity to fail due to poor blood compatibility and …
[PDF][PDF] Imparting native blood vessel biomimicry into next-generation vascular grafts: Bioengineered perlecan domain V for vascular cell modulation
A Jiang - 2023 - unsworks.unsw.edu.au
Vascular bypass surgery is a common clinical intervention for occlusions caused by
atherosclerosis. Synthetic vascular grafts are used when a suitable native vessel is absent …
atherosclerosis. Synthetic vascular grafts are used when a suitable native vessel is absent …
[PDF][PDF] Biofunctionalisation of surface modified silk biomaterials towards creating biomimetic vascular conduits
K Lau - 2021 - unsworks.unsw.edu.au
Cardiovascular disease is the leading cause of death globally, mainly due to blood vessel
occlusions resulting in tissue necrosis and ischaemic strokes. When pharmacological …
occlusions resulting in tissue necrosis and ischaemic strokes. When pharmacological …