Candidate biomarkers in psychiatric disorders: state of the field

A Abi‐Dargham, SJ Moeller, F Ali… - World …, 2023 - Wiley Online Library
The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …

Towards a biologically annotated brain connectome

V Bazinet, JY Hansen, B Misic - Nature reviews neuroscience, 2023 - nature.com
The brain is a network of interleaved neural circuits. In modern connectomics, brain
connectivity is typically encoded as a network of nodes and edges, abstracting away the rich …

Ensemble model for diagnostic classification of Alzheimer's disease based on brain anatomical magnetic resonance imaging

YF Khan, B Kaushik, CL Chowdhary, G Srivastava - Diagnostics, 2022 - mdpi.com
Alzheimer's is one of the fast-growing diseases among people worldwide leading to brain
atrophy. Neuroimaging reveals extensive information about the brain's anatomy and …

Functional connectome–based predictive modeling in autism

C Horien, DL Floris, AS Greene, S Noble, M Rolison… - Biological …, 2022 - Elsevier
Autism is a heterogeneous neurodevelopmental condition, and functional magnetic
resonance imaging–based studies have helped advance our understanding of its effects on …

Disrupted network integration and segregation involving the default mode network in autism spectrum disorder

B Yang, M Wang, W Zhou, X Wang, S Chen… - Journal of Affective …, 2023 - Elsevier
Abstract Changes in the brain's default mode network (DMN) in the resting state are closely
related to autism spectrum disorder (ASD). Module segmentation can effectively elucidate …

Brain functional activity-based classification of autism spectrum disorder using an attention-based graph neural network combined with gene expression

Z Wang, Y Xu, D Peng, J Gao, F Lu - Cerebral Cortex, 2023 - academic.oup.com
Autism spectrum disorder (ASD) is a complex brain neurodevelopmental disorder related to
brain activity and genetics. Most of the ASD diagnostic models perform feature selection at …

Meta-connectomic analysis maps consistent, reproducible, and transcriptionally relevant functional connectome hubs in the human brain

Z Xu, M Xia, X Wang, X Liao, T Zhao, Y He - Communications Biology, 2022 - nature.com
Human brain connectomes include sets of densely connected hub regions. However, the
consistency and reproducibility of functional connectome hubs have not been established to …

Comprehensive exploration of multi-modal and multi-branch imaging markers for autism diagnosis and interpretation: insights from an advanced deep learning model

J Gao, Y Xu, Y Li, F Lu, Z Wang - Cerebral Cortex, 2024 - academic.oup.com
Autism spectrum disorder is a complex neurodevelopmental condition with diverse genetic
and brain involvement. Despite magnetic resonance imaging advances, autism spectrum …

A study of genetic heterogeneity in autism spectrum disorders based on plasma proteomic and metabolomic analysis: multiomics study of autism heterogeneity

X Tang, C Feng, Y Zhao, H Zhang, Y Gao, X Cao… - MedComm, 2023 - Wiley Online Library
Genetic heterogeneity poses a challenge to research and clinical translation of autism
spectrum disorder (ASD). In this study, we conducted a plasma proteomic and metabolomic …

Deep learning based joint fusion approach to exploit anatomical and functional brain information in autism spectrum disorders

S Saponaro, F Lizzi, G Serra, F Mainas, P Oliva… - Brain Informatics, 2024 - Springer
Background: The integration of the information encoded in multiparametric MRI images can
enhance the performance of machine-learning classifiers. In this study, we investigate …