Microbiome data predictive analysis within a machine learning (ML) workflow presents
numerous domain-specific challenges involving preprocessing, feature selection, predictive …

The gastrointestinal tract is home to the largest microbial population in the human body. The
gut microbiota plays significant roles in the development of the gut immune system and has …

Musculoskeletal diseases affect up to 20% of adults worldwide. The gut microbiome has
been implicated in inflammatory conditions, but large-scale metagenomic evaluations have …

Spondyloarthritis (SpA) refers to a group of diseases with inflammation in joints and spines.
In this family, ankylosing spondylitis (AS) is a rare but classic form that mainly involves the …

Abstract Purpose of Review To commemorate the 50th anniversary of the groundbreaking
discovery of a remarkably strong association between HLA-B* 27 and ankylosing spondylitis …

The 'MHC-I (major histocompatibility complex class I)-opathy'concept describes a family of
inflammatory conditions with overlapping clinical manifestations and a strong genetic link to …

A growing amount of evidence suggests that gut microbiota plays an important role in
human health, including a possible role in the pathogenesis of rheumatic and …

Spondyloarthritis (SpA) is a chronic inflammatory disease that affects the axial skeleton
(axSpA) and/or the peripheral joints (p-SpA) and entheses. The natural history of SpA in the …

Ankylosing spondylitis (AS) is an autoinflammatory disease that manifests with the unique
feature of enthesitis. Gut microbiota, HLA-B* 27, and biomechanical stress mutually …

OBJECTIVES: Spondyloarthritis (SpA) is a group of immune-mediated diseases highly
concomitant with non-musculoskeletal inflammatory disorders, such as acute anterior uveitis …