Impaired diastolic function after exchange of endogenous troponin I with C-terminal truncated troponin I in human cardiac muscle

NA Narolska, N Piroddi, A Belus, NM Boontje… - Circulation …, 2006 - Am Heart Assoc
The specific and selective proteolysis of cardiac troponin I (cTnI) has been proposed to play
a key role in human ischemic myocardial disease, including stunning and acute pressure …

[PDF][PDF] Effect of contractile protein alterations on cardiac myofilament function in human heart failure

NA Narolska - 2006 - research.vu.nl
Cardiac energetics and performance depend on the expression level of the fast (α-) and
slow (β-) myosin heavy chain (MHC) isoform. In ventricular tissue the β-MHC isoform …