The majority of the genome in animals and plants is transcribed in a developmentally
regulated manner to produce large numbers of non–protein-coding RNAs (ncRNAs), whose …

Non-protein-coding sequences increasingly dominate the genomes of multicellular
organisms as their complexity increases, in contrast to protein-coding genes, which remain …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

It appears that the genetic programming of humans and other complex organisms has been
misunderstood for the past 50 years, due to the assumption that most genetic information is …

The family of Hox genes, which number 4 to 48 per genome depending on the animal,
control morphologies on the main body axis of nearly all metazoans. The conventional …

Genome-wide analyses of the eukaryotic transcriptome have revealed that the majority of
the genome is transcribed, producing large numbers of non-protein-coding RNAs (ncRNAs) …

Cystic fibrosis is a genetic disorder that results in a multi‐organ disease with progressive
respiratory decline which leads to premature death. Mutations in the cystic fibrosis …

Chromosome rearrangements may distort 3D chromatin architectures and thus change gene
regulation, yet how 3D chromatin structures evolve in insects is largely unknown. Here, we …

Background The ancestral arthropod is believed to have had a clustered arrangement of ten
Hox genes. Within arthropods, Hox gene mutations result in transformation of segment …

Among chelicerates, Hox gene expression has only been investigated in representatives of
two arachnid orders to date: Acari (mites and ticks) and Araneae (spiders). Limited data are …