Amino acids are natural compounds that can be safely used in pharmaceutical applications.
Considering the great interest in the amino acids used in the pharmaceutical industry, this …

The most favored approach for drug administration is the oral route. Several anticancer
drugs come under this category and mostly lack solubility and oral bioavailability, which are …

The present work-study the improvement of the loading and release efficiency of sofosbuvir
drug (SOF) for anti-hepatitis C virus (HCV) by the combination process with β-cyclodextrin …

The target of the current study is to create a novel hybrid nanocomposite (Cs@ Pyc. SOF) by
combining the anti-hepatitis C virus (HCV) drug sofosbuvir with the nano antioxidant …

Poor solubility limits the pharmacological activities of betamethasone (BM), including its anti-
inflammatory and anti-allergic effects. To improve the aqueous solubility and dissolution rate …

This study aimed to design and characterize Tofacitinib (TF)-loaded lyotropic liquid
crystalline nanoparticles (TF-LCNP) gel using quality by design-driven approach to enhance …

Understanding drug solubility in various solvents is of great importance to the
pharmaceutical industry for design of the process. To date, various modeling approaches …

Hydrogels have been extensively investigated to identify innovative formulations that can
fulfill all the necessary purposes to improve local vaginal therapy through the mucosa …

The study aims to improve the solubility of poorly soluble drug by developing an optimized
formulation of nanocrystals and extend its release profile by incorporating optimized …

The oral bioavailability of poorly soluble drugs has always been the focus of pharmaceutical
researchers. We innovatively combined nanocrystal technology and solid dispersion …