Selfish: discovery of differential chromatin interactions via a self-similarity measure
Motivation High-throughput conformation capture experiments, such as Hi-C provide
genome-wide maps of chromatin interactions, enabling life scientists to investigate the role …
genome-wide maps of chromatin interactions, enabling life scientists to investigate the role …
3D chromatin architecture remodeling during human cardiomyocyte differentiation reveals a novel role of HERV-H in demarcating chromatin domains
Restructuring of chromatin architecture is an essential process for establishing cell type-
specific gene regulatory programs in eukaryotic cells including cardiomyocytes–. Supporting …
specific gene regulatory programs in eukaryotic cells including cardiomyocytes–. Supporting …
Allele-specific NKX2-5 binding underlies multiple genetic associations with human EKG traits
P Benaglio, A D'Antonio-Chronowska, WW Greenwald… - BioRxiv, 2018 - biorxiv.org
Genetic variation affecting the binding of transcription factors (TFs) has been proposed as a
major mechanism underlying susceptibility to common disease. NKX2-5, a key cardiac …
major mechanism underlying susceptibility to common disease. NKX2-5, a key cardiac …
[图书][B] Efficient Algorithms for the Analysis of Hi-C Contact Maps
AR Ardakany - 2019 - search.proquest.com
This dissertation deals with the analysis of high-throughput chromatin conformation capture
(Hi-C) data. Hi-C experiments provide genome-wide maps of chromatin interactions and has …
(Hi-C) data. Hi-C experiments provide genome-wide maps of chromatin interactions and has …
Efficient Algorithms for the Analysis of Hi-C Contact Maps
A Roayaei Ardakany - 2019 - escholarship.org
This dissertation deals with the analysis of high-throughput chromatin conformation capture
(Hi-C) data. Hi-C experiments provide genome-wide maps of chromatin interactions and has …
(Hi-C) data. Hi-C experiments provide genome-wide maps of chromatin interactions and has …
Human iPSC-derived retinal pigment epithelium: a model system for identifying and functionally characterizing causal variants at AMD risk loci
EN Smith, A D'Antonio-Chronowska, WW Greenwald… - bioRxiv, 2018 - biorxiv.org
We evaluate whether human induced pluripotent stem cell-derived retinal pigment
epithelium (iPSC-RPE) cells can be used to prioritize and functionally characterize causal …
epithelium (iPSC-RPE) cells can be used to prioritize and functionally characterize causal …