[HTML][HTML] Technologies for HIV-1 drug resistance testing: inventory and needs
KJ Metzner - Current Opinion in HIV and AIDS, 2022 - journals.lww.com
The use of NGS technologies on HIV DR testing will allow unprecedented insights into
genomic structures of virus populations that may be of immediate relevance to both clinical …
genomic structures of virus populations that may be of immediate relevance to both clinical …
HIV-1 drug resistance genotyping in resource limited settings: current and future perspectives in sequencing technologies
Affordable, sensitive, and scalable technologies are needed for monitoring antiretroviral
treatment (ART) success with the goal of eradicating HIV-1 infection. This review discusses …
treatment (ART) success with the goal of eradicating HIV-1 infection. This review discusses …
Next‐Generation Sequencing Methods for Near‐Real‐Time Molecular Epidemiology of HIV and HCV
BA Horsburgh, GJ Walker, A Kelleher… - Reviews in Medical …, 2024 - Wiley Online Library
ABSTRACT The World Health Organisation has set targets of reducing the transmission of
new hepatitis C (HCV) infections by 90%, and ending human immunodeficiency virus‐1 …
new hepatitis C (HCV) infections by 90%, and ending human immunodeficiency virus‐1 …
[HTML][HTML] Laboratory diagnosis of HIV: a contemporary overview in the Australian context
E Williams, M Moso, C Lim, D Chibo, S Nicholson… - Pathology, 2023 - Elsevier
Over the past decade there have been technical advances in human immunodeficiency
virus (HIV) assays and updates to testing regulations that have substantially changed the …
virus (HIV) assays and updates to testing regulations that have substantially changed the …
Low-frequency pre-treatment HIV drug resistance: Effects on 2-year outcome of first-line efavirenz-based antiretroviral therapy
RS Milne, IA Beck, M Levine, I So, N Andersen… - Aids, 2022 - journals.lww.com
Objective (s): Assess the impact of pre-treatment high-frequency and low-frequency drug-
resistant HIV variants on long-term outcomes of first-line efavirenz-based antiretroviral …
resistant HIV variants on long-term outcomes of first-line efavirenz-based antiretroviral …
Viral resistance burden and APOBEC editing correlate with virological response in heavily treatment-experienced people living with multi-drug resistant HIV
D Armenia, MM Santoro, MC Bellocchi, L Carioti… - International Journal of …, 2022 - Elsevier
Background The impact of drug resistance mutational load and APOBEC editing in heavily
treatment-experienced (HTE) people living with multidrug-resistant HIV has not been …
treatment-experienced (HTE) people living with multidrug-resistant HIV has not been …
Advancing HIV drug resistance technologies and strategies: insights from South Africa's experience and future directions for resource-limited settings
Monitoring of HIV drug resistance (HIVDR) remains critical for ensuring countries attain and
sustain the global goals for ending HIV as a public health threat by 2030. On an individual …
sustain the global goals for ending HIV as a public health threat by 2030. On an individual …
Strengths and caveats of identifying resistance genes from whole genome sequencing data
Introduction Antimicrobial resistance (AMR) continues to present major challenges to
modern healthcare. Recent advances in whole-genome sequencing (WGS) have made the …
modern healthcare. Recent advances in whole-genome sequencing (WGS) have made the …
Portable Nanopore sequencing solution for next-generation HIV drug resistance testing
SY Park, G Faraci, K Ganesh, MP Dubé… - Journal of Clinical …, 2024 - Elsevier
Background Tackling HIV drug resistance is one of major challenges for ending AIDS
epidemic, but the elevated expense of cutting-edge genomics hampers the advancement of …
epidemic, but the elevated expense of cutting-edge genomics hampers the advancement of …
[HTML][HTML] Comparative Evaluation of Open-Source Bioinformatics Pipelines for Full-Length Viral Genome Assembly
The increasingly widespread application of next-generation sequencing (NGS) in clinical
diagnostics and epidemiological research has generated a demand for robust, fast …
diagnostics and epidemiological research has generated a demand for robust, fast …