Highlights•Endolysosomal organelles are dynamically distributed throughout the cytoplasm.•Movement of endolysosomal organelles depends on coupling to microtubule …
JL Watson, E Seinkmane, CT Styles, A Mihut… - Nature, 2023 - nature.com
Optimum protein function and biochemical activity critically depends on water availability because solvent thermodynamics drive protein folding and macromolecular interactions …
Ordered two-dimensional arrays such as S-layers, and designed analogues,–have intrigued bioengineers,, but with the exception of a single lattice formed with flexible linkers, they are …
M Liu, Q Li, L Liang, J Li, K Wang, J Li, M Lv… - Nature …, 2017 - nature.com
Mechanistic understanding of the endocytosis and intracellular trafficking of nanoparticles is essential for designing smart theranostic carriers. Physico-chemical properties, including …
ZG Venkei, YM Yamashita - Journal of Cell Biology, 2018 - rupress.org
The asymmetric cell division of stem cells, which produces one stem cell and one differentiating cell, has emerged as a mechanism to balance stem cell self-renewal and …
Asymmetric cell division (ACD) is an evolutionarily conserved mechanism used by prokaryotes and eukaryotes alike to control cell fate and generate cell diversity. A detailed …
Eukaryotic cells face the challenging task of transporting a variety of particles through the complex intracellular milieu in order to deliver, distribute, and mix the many components that …
Polarized cells rely on a polarized cytoskeleton to function. Yet, how cortical polarity cues induce cytoskeleton polarization remains elusive. Here, we capitalized on recently …
M Romanova-Michaelides, Z Hadjivasiliou… - Nature, 2022 - nature.com
Morphogen gradients are fundamental to establish morphological patterns in developing tissues. During development, gradients scale to remain proportional to the size of growing …