Anthracyclines have been important and effective treatments against a number of cancers
since their discovery. However, their use in therapy has been complicated by severe side …

Among cancers, breast cancer has the highest incidence rate among women and poses a
tremendous threat to women's health. Messenger RNA (mRNA), microRNA (miRNA) and …

Cell cycle is one of the main cellular mechanisms involved in tumor progression. Almost all
of the active molecular pathways in tumor cells directly or indirectly target the cell cycle …

Gene therapy can be used as a cancer therapy by affecting signaling networks participating
in the aggressive behavior of tumors. Small interfering RNA (siRNA) is a genetic tool …

Although, there is a high rate of good prognosis in early stage head and neck tumors, about
half of these tumors are detected in advanced stages with poor prognosis. A combination of …

Surgery and chemo-radiotherapy are used as the common first-line treatment options in
many cancers. However, tumor relapse is observed in many cancer patients following such …

Chemotherapy is one of the most common therapeutic methods in advanced and metastatic
tumors. Cisplatin (CDDP) is considered as one of the main first-line chemotherapy drugs in …

The metabolism of human body is mainly regulated by the pancreas, liver, and thyroid using
the hormones or exocrine secretions that affect the metabolic processes from food digestion …

Lung cancer is the second most common and the leading cause of cancer related deaths
globally. Tyrosine Kinase Inhibitors (TKIs) are among the common therapeutic strategies in …

Doxorubicin (DOX) is a cornerstone chemotherapeutic agent for the treatment of several
malignancies such as breast cancer; however, its activity is ameliorated by the development …