Antibodies to the RBD of SARS-CoV-2 spike mediate productive infection of primary human macrophages
S Pickering, H Wilson, E Bravo, MR Perera… - Nature …, 2024 - nature.com
The role of myeloid cells in the pathogenesis of SARS-CoV-2 is well established, in
particular as drivers of cytokine production and systemic inflammation characteristic of …
particular as drivers of cytokine production and systemic inflammation characteristic of …
Proteomics validate circulating GDF-15 as an independent biomarker for COVID-19 severity
Introduction Growth differentiation factor 15 (GDF-15) was originally described as a stress-
induced cytokine, and a biomarker of aging and cardiovascular diseases. We hypothesized …
induced cytokine, and a biomarker of aging and cardiovascular diseases. We hypothesized …
Proteomic characterization of acute kidney injury in patients hospitalized with SARS-CoV2 infection
Background Acute kidney injury (AKI) is a known complication of COVID-19 and is
associated with an increased risk of in-hospital mortality. Unbiased proteomics using …
associated with an increased risk of in-hospital mortality. Unbiased proteomics using …
[HTML][HTML] Impact and prevalence of comorbidities and complications on the severity of COVID-19 in association with age, gender, obesity, and pre-existing smoking: A …
S Djorwé, A Bousfiha, N Nzoyikorera, J Nyandwi… - BioMedicine, 2024 - ncbi.nlm.nih.gov
Background COVID-19 patients usually present multiple comorbidities and complications
associated with severe forms of SARS-CoV-2 infection. This study aimed to assess the risk …
associated with severe forms of SARS-CoV-2 infection. This study aimed to assess the risk …
Proteomic signatures of vaccine-induced and breakthrough infection-induced host responses to SARS-CoV-2
The severity of SARS-CoV-2 illness is influenced by factors including age, sex, pre-existing
health conditions, and individual immune responses. However, the mechanisms conferring …
health conditions, and individual immune responses. However, the mechanisms conferring …
Multi-omics identify LRRC15 as a COVID-19 severity predictor and persistent pro-thrombotic signals in convalescence
Patients with end-stage kidney disease (ESKD) are at high risk of severe COVID-19. Here,
we performed longitudinal blood sampling of ESKD haemodialysis patients with COVID-19 …
we performed longitudinal blood sampling of ESKD haemodialysis patients with COVID-19 …
Multi-ancestry proteome-phenome-wide Mendelian randomization offers a comprehensive protein-disease atlas and potential therapeutic targets
Circulating proteins influence disease risk and are valuable drug targets. To enhance the
discovery of protein-phenotype associations and identify potential therapeutic targets across …
discovery of protein-phenotype associations and identify potential therapeutic targets across …
Longitudinal analysis of the lung proteome reveals persistent repair months after mild to moderate COVID-19
In order to assess homeostatic mechanisms in the lung after COVID-19, changes in the
protein signature of bronchoalveolar lavage from 45 patients with mild to moderate disease …
protein signature of bronchoalveolar lavage from 45 patients with mild to moderate disease …
[PDF][PDF] Proteomic characterization of acute kidney injury in patients hospitalized with SARS-CoV2 infection
AW Charney, GN Nadkarni - d-nb.info
Background Acute kidney injury (AKI) is a known complication of COVID-19 and is
associated with an increased risk of in-hospital mortality. Unbiased proteomics using …
associated with an increased risk of in-hospital mortality. Unbiased proteomics using …
[HTML][HTML] Proteomic Characterization of Acute Kidney Injury in Patients Hospitalized with SARS-CoV2 Infection
Background Acute kidney injury (AKI) is a known complication of COVID-19 and is
associated with an increased risk of in-hospital mortality. Unbiased proteomics using …
associated with an increased risk of in-hospital mortality. Unbiased proteomics using …