Accumulating evidence indicates that inflammatory and immunologic processes play a
significant role in the development and progression of glomerular diseases. Podocytes, the …

Focal segmental glomerulosclerosis (FSGS) is a common glomerular disorder that manifests
clinically with the nephrotic syndrome and has a propensity to recur following kidney …

Podocyte injury is a hallmark of glomerular diseases; however, the underlying mechanisms
remain unclear. B7-1 is increased in injured podocytes, but its intrinsic role is controversial …

Idiopathic nephrotic syndrome is the most common childhood glomerular disease. Most
forms of this syndrome respond to corticosteroids at standard doses and are, therefore …

Minimal change disease (MCD) is the most common type of idiopathic nephrotic syndrome
in childhood and represents about 15% cases in adults. It is characterized by massive …

Background Nephrotic syndrome is a common complication of pig‐to‐baboon kidney
xenotransplantation (KXTx) that adversely affects outcomes. We have reported that …

Introduction Minimal change disease (MCD) is considered a podocyte disorder triggered by
unknown circulating factors. Here, we hypothesized that the endothelial cell (EC) is also …

Introduction Heterogeneity of nephrotic diseases and a lack of validated biomarkers limits
interventions and reduces the ability to examine outcomes. Urinary CD80 is a potential …

Minimal change disease (MCD) is the most common cause of idiopathic nephrotic syndrome
in children, and it is well known for its multifactorial causes which are the manifestation of the …

Glomerular diseases are often chronic or recurring and thus associated with a tremendous
physical, psychological, and economic burden. Their etiologies are often unknown, and their …