This review classifies and summarizes the past 10–15 years of advancements in the field of
metal-involving (ie, metal-mediated and metal-catalyzed) reactions of oximes. These …

The methodology for peptide bond formation is undergoing a continuous evolution where
the main actors are being renewed. In recent years, coupling reagents based on the Oxyma …

A mild, practical, and simple procedure for phenyl selenoesters synthesis from several
anhydrides and diphenyl diselenide was developed. This transition-metal-free method …

6-(3, 5-Bis (trifluoromethyl) phenyl)-1 H, 4 H-2aλ3-ioda-2, 3-dioxacyclopenta [hi] indene-1, 4-
dione (p-BTFP-iodosodilactone, 1a) was synthesized and demonstrated to be an efficient …

A mild method is described for the conversion of carboxylic acids into esters, amides, as well
as peptides without racemization through carboxyl activation by the reagent combination of …

OxymaPure [ethyl 2-cyano-2-(hydroxyimino) acetate] is an exceptional reagent with which to
suppress racemization and enhance coupling efficiency during amide bond formation. The …

A reliable, scalable, cost-effective, and chromatography-free synthesis of 4-azido-l-
phenylalanine beginning from l-phenylalanine is described. Investigations into the safety of …

Here we present a new formulation of the recently introduced OxymaPure additive for
peptide bond formation, in which the N‐hydroxylamine group is replaced by a potassium …

A metal‐free and catalytic method for the synthesis of 2‐substituted benzoxazoles and
benzothiazoles from N‐protected amino acids and carboxylic acids is described. The …

Abstract Boc‐Oxyma (Ethyl 2‐(tert‐butoxycarbonyloxyimino)‐2‐cyanoacetate) has been
reported previously as an efficient coupling reagent for the synthesis of amides, peptides …