Transition-metal-catalyzed nucleophilic addition of organometallic reagents to polar
unsaturated substrates is one of the most important and powerful bond-forming strategies …

Quinolines and their derivatives have always been promising leads for drug discovery,
material applications and designing new catalysts. In the past decade, C (sp3)‐H …

addition reactions of alkylazaarenes catalyzed by strong Brønsted bases have been
developed for the first time. The desired reactions with α, β‐unsaturated amides proceeded …

The catalyst-free sp3 C–H functionalization of 2-alkylazaarenes has been achieved in the
reaction with (thio) coumarin-3-carboxylic acids. Followed by a tandem decarboxylation, this …

Bioactive azaarene-substituted lactic acids, β-hydroxy esters, 3-hydroxy-2H-indol-2-ones,
and 2-alkenylazaarenes were prepared in moderate-to-excellent yields via C (sp3)–H …

SN1-Type Alkylation of N-Heteroaromatics with Alcohols | Organic Letters ACS ACS Publications
C&EN CAS Find my institution Log In Organic Letters ACS Publications. Most Trusted. Most Cited …

This Letter described a facile approach to synthesize (E)-2-alkenylquinoline derivatives via
C (sp 3)-H functionalization of 2-methylquinolines under catalyst-free conditions. A variety of …

Transition‐metal mediated activation of inert chemical bonds is an ongoing topic in
homogeneous catalysis. In view of the abundance and accessibility of alkylarenes and …

A novel and efficient protocol has been developed for the synthesis of azaarene-substituted
3-hydroxy-2-oxindoles via sp3 C–H functionalization of 2-methyl azaarenes and (2-azaaryl) …

A facile catalyst-free tandem sp3 C–H functionalization/decarboxylation of 4-oxo-4H-
chromene-3-carboxylic acid with 2-alkylazaarenes was developed, which can efficiently …