Simple Summary In the fight against cancer, immunotherapies have given great hope after
encouraging results in clinical investigations showing complete remission in some patients …

Survival of gastrointestinal cancer remains dismal, especially for metastasized disease. For
various cancers, especially melanoma and lung cancer, immunotherapy has been proven to …

Cytokine therapy for cancer has indicated efficacy in certain diseases but is generally
accompanied by severe toxicity. The field of antibody–cytokine fusion proteins …

Finding improved therapeutic strategies against T-cell Non-Hodgkin's Lymphoma (NHL)
remains an unmet clinical need. We implemented a theranostic approach employing a tumor …

Rationale Murine syngeneic tumor models have revealed efficacious systemic antitumor
responses following primary tumor in situ vaccination combined with targeted radionuclide …

Targeted radionuclide therapy (TRT) and immunotherapy are rapidly growing classes of
cancer treatments. Basic, translational, and clinical research are now investigating …

An updated survival analysis by Callahan et al. published in the February 1, 2018 issue of
the Journal of Clinical Oncology reported a 3-year overall survival (OS) rate of 63% for 94 …

Simple Summary Radiation therapy and immune checkpoint inhibitors (ICIs) have been
demonstrated to cooperatively activate adaptive anti-tumor immunity with curative potential …