Neuroendocrine neoplasms (NENs) comprise well-differentiated neuroendocrine tumors
(NETs) and poorly differentiated neuroendocrine carcinomas (NECs). Treatment options for …

Thoracic (pulmonary and thymic) neuroendocrine tumors are well-differentiated epithelial
neuroendocrine neoplasms that are classified into typical and atypical carcinoid tumors …

Lung neuroendocrine neoplasms (NENs) encompass a spectrum of neoplasms that are
subdivided into the well-differentiated neuroendocrine tumors comprising the low-and …

Pulmonary neuroendocrine cells (PNECs) are sensory epithelial cells that transmit airway
status to the brain via sensory neurons and locally via calcitonin gene-related peptide …

Background Organoids are 3-dimensional experimental models that summarize the
anatomical and functional structure of an organ. Although a promising experimental model …

Studies have shown that Nrf2 E79Q/+ is one of the most common mutations found in human
tumors. To elucidate how this genetic change contributes to lung cancer, we compared lung …

Lung carcinoid tumors, also referred to as pulmonary neuroendocrine tumors or lung
carcinoids, are rare neoplasms of the lung with a more favorable prognosis than other …

Background Malignant pleural mesothelioma (MPM) is a rare understudied cancer
associated with exposure to asbestos. So far, MPM patients have benefited marginally from …

High-throughput technologies used in molecular biology have been pivotal to enhance the
molecular characterization of human malignancies, allowing multiple omics data types to be …

The genetic characteristics of rectal neuroendocrine tumors (R-NETs) were poorly
understood. Depicting the genetic characteristics may provide a biological basis for …