[HTML][HTML] Conventional methods and future trends in antimicrobial susceptibility testing

MA Salam, MY Al-Amin, JS Pawar, N Akhter… - Saudi journal of …, 2023 - Elsevier
Antimicrobial susceptibility testing is an essential task for selecting appropriate antimicrobial
agents to treat infectious diseases. Constant evolution has been observed in methods used …

Biofilm antimicrobial susceptibility testing: where are we and where could we be going?

T Coenye - Clinical microbiology reviews, 2023 - Am Soc Microbiol
Our knowledge about the fundamental aspects of biofilm biology, including the mechanisms
behind the reduced antimicrobial susceptibility of biofilms, has increased drastically over the …

[PDF][PDF] Cyclic-di-GMP signaling controls metabolic activity in Pseudomonas aeruginosa

M Lichtenberg, KN Kragh, B Fritz, JB Kirkegaard… - Cell reports, 2022 - cell.com
Bacteria in biofilms are embedded in extracellular matrix and display low metabolic activity,
partly due to insufficient diffusive exchange of metabolic substrate. The extracellular matrix …

[HTML][HTML] Current and future flow cytometry applications contributing to antimicrobial resistance control

LG Marutescu - Microorganisms, 2023 - mdpi.com
Antimicrobial resistance is a global threat to human health and welfare, food safety, and
environmental health. The rapid detection and quantification of antimicrobial resistance are …

Effective antimicrobial combination in vivo treatment predicted with microcalorimetry screening

KN Kragh, D Gijón, A Maruri, A Antonelli… - Journal of …, 2021 - academic.oup.com
Objectives The worldwide emergence of antibiotic resistance calls for effective exploitation
of existing antibiotics. Antibiotic combinations with different modes of action can synergize …

Isothermal microcalorimetry vs checkerboard assay to evaluate in-vitro synergism of meropenem–amikacin and meropenem–colistin combinations against multi-drug …

A Antonelli, M Coppi, C Tellapragada, B Hasan… - International Journal of …, 2022 - Elsevier
Objectives To evaluate the activity of meropenem–amikacin and meropenem–colistin
combinations with checkerboard broth microdilution (CKBM) compared with isothermal …

[HTML][HTML] Polymyxin B stabilized DNA micelles for sustained antibacterial and antibiofilm activity against P. aeruginosa

A Sousa, V Borøy, A Bæverud, K Julin… - Journal of Materials …, 2023 - pubs.rsc.org
Nucleic acid-based materials showcase an increasing potential for antimicrobial drug
delivery. Although numerous reports on drug-loaded DNA nanoparticles outline their pivotal …

The quorum-sensing inhibitor furanone C-30 rapidly loses its tobramycin-potentiating activity against Pseudomonas aeruginosa biofilms during experimental evolution

M Bové, X Bao, A Sass, A Crabbé… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
The use of quorum-sensing inhibitors (QSI) has been proposed as an alternative strategy to
combat antibiotic resistance. QSI reduce the virulence of a pathogen without killing it and it is …

[HTML][HTML] Unraveling resistance mechanisms in combination therapy: A comprehensive review of recent advances and future directions

N Morales-Durán, A León-Buitimea… - Heliyon, 2024 - cell.com
Antimicrobial resistance is a global health threat. Misuse and overuse of antimicrobials are
the main drivers in developing drug-resistant bacteria. The emergence of the rapid global …

[HTML][HTML] Adjunctive Use of Phage Sb-1 in Antibiotics Enhances Inhibitory Biofilm Growth Activity versus Rifampin-Resistant Staphylococcus aureus Strains

L Wang, T Tkhilaishvili, A Trampuz - Antibiotics, 2020 - mdpi.com
Effective antimicrobials are crucial for managing Staphylococcus aureus implant-associated
bone infections (IABIs), particularly for infections due to rifampin-resistant S. aureus (RRSA) …