The role of dendritic spines in epileptogenesis

G Jean, J Carton, K Haq, AE Musto - Frontiers in Cellular …, 2023 - frontiersin.org
Epilepsy is a chronic central nervous system (CNS) disease associated with high morbidity.
To date, there is no known disease-modifying therapy for epilepsy. A leading hypothesis for …

Synaptic alterations and neuronal firing in human epileptic neocortical excitatory networks

R Bod, K Tóth, N Essam, EZ Tóth, L Erõss… - Frontiers in Synaptic …, 2023 - frontiersin.org
Epilepsy is a prevalent neurological condition, with underlying neuronal mechanisms
involving hyperexcitability and hypersynchrony. Imbalance between excitatory and inhibitory …

[PDF][PDF] Ultrastructural Changes in Brain Tissue in Drug-Resistant Mesial Temporal Lobe Epilepsy in Humans: A Mini-Review

D Sitovskaya, Y Zabrodskaya - Journal ISSN, 2023 - researchgate.net
Epilepsy is a group of chronic neurological diseases of the brain characterized by a
persistent predisposition to epileptic seizures, affecting more than 70 million people …

Sex Differences in Parvalbumin Inhibitory Interneurons in the Mouse Retrosplenial Cortex

NK Khiabanian - 2024 - prism.ucalgary.ca
Parvalbumin inhibitory interneurons (PV-INs) are a crucial subclass of cortical interneurons,
essential for maintaining excitatory/inhibitory (E/I) balance. Disruptions in E/I balance can …

[PDF][PDF] Different Aspects of Electrophysiological and Quantitative Electron Microscopic Investigations in the Rat and the Human Neocortex

EZ Tóth - 2024 - repo.lib.semmelweis.hu
Nowadays, we have the opportunity to choose from a wide range of methods for
investigating the brain. With technological advances, more and more rather complicated …