Protein-coding and noncoding genes in eukaryotes are typically expressed as linear
messenger RNAs, with exons arranged colinearly to their genomic order. Recent advances …

It has recently been reported that thousands of covalently linked circular RNAs (circRNAs)
are expressed from human genomes. circRNAs emerge during RNA splicing. circRNAs are …

Background New noninvasive and affordable molecular approaches that will complement
current practices and increase the accuracy of Parkinson's disease (PD) diagnosis are …

Parkinson's disease (PD) is a complex, age-related, neurodegenerative disease whose
etiology, pathology, and clinical manifestations remain incompletely understood. As a result …

Spheroidal cancer cell cultures have been used to enrich cancer stem cells (CSC), which
are thought to contribute to important clinical features of tumors. This study aimed to map the …

As a newly discovered type of RNA, circular RNAs (circRNAs) are widespread throughout
the eukaryotic genome. The expression of circRNAs is regulated by both cis-elements and …

As part of the superfamily of long noncoding RNAs, circular RNAs (circRNAs) are emerging
as a new type of regulatory molecules that partake in gene expression control. Here, we …

Mutations in U2AF1 are relatively common in myelodysplastic neoplasms (MDS) and are
associated with an inferior prognosis, but the molecular mechanisms underlying this are not …

Preeclampsia (PE) is a multiple organ and system disease that seriously threatens the safety
of the mother and infant during pregnancy, and has a profound impact on the morbidity and …

Background Programmed ribosomal frameshifting (PRF) is a gene expression mechanism
which enables the translation of two N-terminally coincident, C-terminally distinct protein …