Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease characterized by
inflammation of the synovial tissue and joint bone destruction, often leading to significant …

Inflammaging, a coexistence of inflammation and aging, is a persistent, systemic, low-grade
inflammation seen in the geriatric population. Various natural compounds have been greatly …

Age-associated osteosarcopenia is an unresolved syndrome characterized by the
concomitant loss of bone (osteopenia) and skeletal muscle (sarcopenia) tissues increasing …

Background Activated osteoclasts cause excessive bone resorption, and disrupt bone
homeostasis, leading to osteoporosis. The extracellular signal-regulated kinase (ERK) …

Berberine is a phytocompound from plants viz. Phellodendri cortex and Coptis rhizome,
used to treat a variety of diseases. It is effective in preventing osteoporosis, but it is less …

Mitogen-activated protein kinase (MAPK), a serine/threonine-specific protein kinase, is
known to be involved in biomedical signaling mechanisms. In this study, biomedical activity …