Focusing on the literature progress since 2002, the present review explores the highly
significant role that multicomponent reactions (MCRs) have played as a very important tool …

Ultrasonic irradiation serves as a vigorous and environmentally sustainable approach for
augmenting multicomponent reactions (MCRs), offering benefits such as thermal …

N-heterocyclic scaffolds represent a privileged architecture in the process of drug design
and development. It has widespread occurrence in synthetic and natural products, either …

Because of their extraordinary ability to disrupt the natural structure of nucleic acids, metal
complexes could be used in cancer therapy. In this study, cyclohexylglycine (HL) as a ligand …

In the last two decades, the search for sustainability in chemical reactions has attached a lot
of attention. In this focus review, the use of ultrasound (US) as an alternative energy source …

The pyrimidine scaffold is present in many bioactive drugs; therefore, efficient synthetic
routes that provide shorter reaction times, higher yields, and site-selective reactions are …

The inhibition of D-alanine-D-alanine ligase (Ddl) prevents bacterial growth, which makes
this enzyme an attractive and viable target in the urgent search for novel effective …

The widespread scrutiny of orthodox synthetic techniques for the fabrication of nitrogen-
embracing heteroatom segments has shifted scholar's focus to innovative environmentally …

Chalcone‐derived pyrimidine is a well‐known heterocyclic compound that is commonly
present in ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) bio‐isosteres …

Herein, we report an environmentally friendly, rapid, and convenient ionic liquid
([Et3NH][HSO4])-promoted facile synthesis of ethyl 4-(6-substituted-4-oxo-4H-chromen-3-yl) …