Covering: 2013 up to the end of 2015 This review covers the isolation and structure of new
pyrrolizidines; pyrrolizidine biosynthesis; biological activity, including the occurrence of …

The Horner-Wadsworth-Emmons reaction is one of the most reliable and widespread
synthetic tools for the stereocontrolled construction of ethylenic bonds. The versatility of the …

Naturally occurring pyrrolizidine alkaloids (PAs) are isolated from plants and other sources.
The interest of the scientific community in these compounds owes itself to their high toxicity …

Pyrrolizidine or azabicyclo [3.3. 0]-octane (Figure 1) and its derivatives are a very common
azabicycle motif within natural products (pyrrolizidine alkaloids, PAs) possessing a bridge …

A simple and highly efficient approach to hydroxylated pyrrolizidine and indolizidine is
developed from an aldehyde as a starting material using organocatalytic and asymmetric …

The syntheses of several alkaloids and nitrogen-containing compounds including N-Boc-
coniine (14b), pyrrolizidine (1), δ-coniceine (2), and pyrrolo [1, 2 a] azepine (3) are …

The direct α-amination of carbonyl compounds using organocatalysts represents a powerful
and atom-economical tool for asymmetric C–N bond formation. We describe a complete …

A general organocatalytic strategy for asymmetric synthesis of both syn/anti-1, 3-diamines
has been developed. The strategy employs proline-catalyzed sequential α-amination and …

Flash vacuum pyrolysis (FVP) of twelve acetylenic amides was investigated. Products of
pyrolysis were analyzed, characterized, and mechanisms for their thermal behavior were …

A practical and efficient organocatalytic approach to the synthesis of substituted piperidine
alkaloids in high enantio-and diastereomeric excess was achieved using proline-catalyzed …