Less label, more free: approaches in label‐free quantitative mass spectrometry
In this review we examine techniques, software, and statistical analyses used in label‐free
quantitative proteomics studies for area under the curve and spectral counting approaches …
quantitative proteomics studies for area under the curve and spectral counting approaches …
Semantic similarity in biomedical ontologies
In recent years, ontologies have become a mainstream topic in biomedical research. When
biological entities are described using a common schema, such as an ontology, they can be …
biological entities are described using a common schema, such as an ontology, they can be …
DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)
BT Sherman, M Hao, J Qiu, X Jiao… - Nucleic acids …, 2022 - academic.oup.com
DAVID is a popular bioinformatics resource system including a web server and web service
for functional annotation and enrichment analyses of gene lists. It consists of a …
for functional annotation and enrichment analyses of gene lists. It consists of a …
Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy
CX Dominguez, S Müller, S Keerthivasan, H Koeppen… - Cancer discovery, 2020 - AACR
With only a fraction of patients responding to cancer immunotherapy, a better understanding
of the entire tumor microenvironment is needed. Using single-cell transcriptomics, we chart …
of the entire tumor microenvironment is needed. Using single-cell transcriptomics, we chart …
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight
INTRODUCTION To date, 559 humans have been flown into space, but long-duration (> 300
days) missions are rare (n= 8 total). Long-duration missions that will take humans to Mars …
days) missions are rare (n= 8 total). Long-duration missions that will take humans to Mars …
Characterization and biomarker analyses of post-COVID-19 complications and neurological manifestations
As the SARS-CoV-2 pandemic continues, reports have demonstrated neurologic sequelae
following COVID-19 recovery. Mechanisms to explain long-term neurological sequelae are …
following COVID-19 recovery. Mechanisms to explain long-term neurological sequelae are …
Neuron-astrocyte metabolic coupling protects against activity-induced fatty acid toxicity
Metabolic coordination between neurons and astrocytes is critical for the health of the brain.
However, neuron-astrocyte coupling of lipid metabolism, particularly in response to neural …
However, neuron-astrocyte coupling of lipid metabolism, particularly in response to neural …
Memory-like NK cells armed with a neoepitope-specific CAR exhibit potent activity against NPM1 mutated acute myeloid leukemia
Acute myeloid leukemia (AML) remains a therapeutic challenge, and a paucity of tumor-
specific targets has significantly hampered the development of effective immune-based …
specific targets has significantly hampered the development of effective immune-based …
pathfindR: an R package for comprehensive identification of enriched pathways in omics data through active subnetworks
Pathway analysis is often the first choice for studying the mechanisms underlying a
phenotype. However, conventional methods for pathway analysis do not take into account …
phenotype. However, conventional methods for pathway analysis do not take into account …
Lung adenocarcinoma and lung squamous cell carcinoma cancer classification, biomarker identification, and gene expression analysis using overlapping feature …
JW Chen, J Dhahbi - Scientific reports, 2021 - nature.com
Lung cancer is one of the deadliest cancers in the world. Two of the most common subtypes,
lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC), have drastically …
lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC), have drastically …