Age-related macular degeneration

SL Fine, JW Berger, MG Maguire… - New England Journal of …, 2000 - Mass Medical Soc
Age-related macular degeneration, a deterioration of the central portion of the retina, is the
chief cause of severe and irreversible loss of vision in developed countries. 1, 2 There is no …

Drug delivery systems for vitreoretinal diseases

T Yasukawa, Y Ogura, Y Tabata, H Kimura… - Progress in retinal and …, 2004 - Elsevier
The eye has an environment that is specific unto itself in terms of pharmacokinetics: the
inner and outer blood–retinal barriers separate the retina and the vitreous from the systemic …

Vascular targeting in photodynamic occlusion of subretinal vessels

U Schmidt-Erfurth, T Hasan, E Gragoudas, N Michaud… - Ophthalmology, 1994 - Elsevier
Purpose: To evaluate the potential of photodynamic therapy (PDT) using benzoporphyrin
derivative (BPD) for occlusion of subretinal neovascular membranes, the authors studied …

Combined photodynamic therapy with verteporfin and intravitreal triamcinolone acetonide for choroidal neovascularization

RF Spaide, J Sorenson, L Maranan - Ophthalmology, 2003 - Elsevier
PURPOSE: To examine combined photodynamic therapy (PDT) with verteporfin and
intravitreal triamcinolone acetonide for choroidal neovascularization (CNV) secondary to …

Photodynamic therapy of subfoveal choroidal neovascularization: clinical and angiographic examples

U Schmidt-Erfurth, J Miller, M Sickenberg… - Graefe's archive for …, 1998 - Springer
Abstract· Background: Conventional photocoagulation of subfoveal choroidal
neovascularization (CNV) is often accompanied by visual loss due to thermal damage to …

Intraocular sustained drug delivery using implantable polymeric devices

T Yasukawa, Y Ogura, E Sakurai, Y Tabata… - Advanced drug delivery …, 2005 - Elsevier
Vitreoretinal diseases involving age-related macular degeneration (AMD) are refractory to
most topical or systemic drugs. The retina and the vitreous cavity have a unique position …

Epidemiology of age-related maculopathy

H Vingerling - 1995 - repub.eur.nl
In 1875, Pagenstecher and Gentll provided the first description of age-related maculopathy
(ARM). Nowadays, hundred and twenty years after the first description, ARM is one of the …

Surgery for subfoveal choroidal neovascularization in age-related macular degeneration: ophthalmic findings: SST report no. 11.

BS Hawkins, NM Bressler, PH Miskala, SB Bressler… - …, 2004 - europepmc.org
Purpose To present visual acuity (VA) and related findings from patients enrolled in one of
the Submacular Surgery Trials (SST) evaluating surgical removal versus observation of …

Age-related macular degeneration: a review of experimental treatments

TA Ciulla, RP Danis, A Harris - Survey of ophthalmology, 1998 - Elsevier
Age-related macular degeneration (AMD) is the leading cause of irreversible visual loss in
the USA. Laser photocoagulation of choroidal neovascular membranes (CNVMs) in …

Age-related macular degeneration: epidemiology and optimal treatment

M la Cour, JF Kiilgaard, MH Nissen - Drugs & aging, 2002 - Springer
Age-related macular degeneration (AMD) is a common macular disease affecting elderly
people in the Western world. It is characterised by the appearance of drusen in the macula …