Circulating tumor DNA in B-cell lymphoma: technical advances, clinical applications, and perspectives for translational research

EM Lauer, J Mutter, F Scherer - Leukemia, 2022 - nature.com
Noninvasive disease monitoring and risk stratification by circulating tumor DNA (ctDNA)
profiling has become a potential novel strategy for patient management in B-cell lymphoma …

PET/CT in non-Hodgkin lymphoma: an update

L Zanoni, D Bezzi, C Nanni, A Paccagnella… - Seminars in nuclear …, 2023 - Elsevier
Non-Hodgkin lymphomas represents a heterogeneous group of lymphoproliferative
disorders characterized by different clinical courses, varying from indolent to highly …

Mutational landscape and tumor burden assessed by cell-free DNA in diffuse large B-cell lymphoma in a population-based study

A Rivas-Delgado, F Nadeu, A Enjuanes… - Clinical Cancer …, 2021 - AACR
Purpose: We analyzed the utility of cell-free DNA (cfDNA) in a prospective population-based
cohort to determine the mutational profile, assess tumor burden, and estimate its impact in …

Prognostic value of baseline metabolic tumor volume and total lesion glycolysis in patients with lymphoma: a meta-analysis

B Guo, X Tan, Q Ke, H Cen - PloS one, 2019 - journals.plos.org
Whether baseline metabolic tumor volume (TMTV) and total lesion glycolysis (TLG)
measured by FDG-PET/CT affected prognosis of patients with lymphoma was controversial …

cfDNA sequencing: technological approaches and bioinformatic issues

E Bohers, PJ Viailly, F Jardin - Pharmaceuticals, 2021 - mdpi.com
In the era of precision medicine, it is crucial to identify molecular alterations that will guide
the therapeutic management of patients. In this context, circulating tumoral DNA (ctDNA) …

Liquid biopsy in lymphoma: Molecular methods and clinical applications

M Cirillo, AFM Craig, S Borchmann, DM Kurtz - Cancer treatment reviews, 2020 - Elsevier
In this article, we broadly review the application of cfDNA analysis to the diagnosis and
management of lymphoma. We introduce the advantages of cfDNA measurement over …

Targeted genotyping of circulating tumor DNA for classical Hodgkin lymphoma monitoring: a prospective study

V Camus, M Viennot, J Lequesne, PJ Viailly… - …, 2020 - pmc.ncbi.nlm.nih.gov
The relevance of circulating tumor DNA (ctDNA) analysis as a liquid biopsy and minimal
residual disease tool in the management of classical Hodgkin lymphoma (cHL) patients was …

Translational application of circulating DNA in oncology: review of the last decades achievements

NO Tuaeva, L Falzone, YB Porozov, AE Nosyrev… - Cells, 2019 - mdpi.com
In recent years, the introduction of new molecular techniques in experimental and clinical
settings has allowed researchers and clinicians to propose circulating-tumor DNA (ctDNA) …

Real-life disease monitoring in follicular lymphoma patients using liquid biopsy ultra-deep sequencing and PET/CT

A Jiménez-Ubieto, M Poza, A Martin-Muñoz… - Leukemia, 2023 - nature.com
In the present study, we screened 84 Follicular Lymphoma patients for somatic mutations
suitable as liquid biopsy MRD biomarkers using a targeted next-generation sequencing …

Quantitative PET-based biomarkers in lymphoma: getting ready for primetime

JP Alderuccio, RA Kuker, F Yang… - Nature Reviews Clinical …, 2023 - nature.com
The use of functional quantitative biomarkers extracted from routine PET–CT scans to
characterize clinical responses in patients with lymphoma is gaining increased attention …