The role of the natural environment in the emergence of antibiotic resistance in Gram-negative bacteria

EMH Wellington, ABA Boxall, P Cross… - The Lancet infectious …, 2013 - thelancet.com
During the past 10 years, multidrug-resistant Gram-negative Enterobacteriaceae have
become a substantial challenge to infection control. It has been suggested by clinicians that …

[HTML][HTML] Extended-spectrum β-lactamase-producing and AmpC-producing Escherichia coli from livestock and companion animals, and their putative impact on public …

C Ewers, A Bethe, T Semmler, S Guenther… - Clinical Microbiology and …, 2012 - Elsevier
The possible zoonotic spread of antimicrobial-resistant bacteria is controversial. This review
discusses global molecular epidemiological data combining both analyses of the …

Evidence of increasing antibiotic resistance gene abundances in archived soils since 1940

CW Knapp, J Dolfing, PAI Ehlert… - Environmental science & …, 2010 - ACS Publications
Mass production and use of antibiotics and antimicrobials in medicine and agriculture have
existed for over 60 years, and has substantially benefited public health and agricultural …

Growing group of extended-spectrum β-lactamases: the CTX-M enzymes

R Bonnet - Antimicrobial agents and chemotherapy, 2004 - Am Soc Microbiol
The production of-lactamases is the predominant cause of resistance to-lactam antibiotics in
gram-negative bacteria. These enzymes cleave the amide bond in the-lactam ring …

Occurrence of ESBL-Producing Escherichia coli in Livestock and Farm Workers in Mecklenburg-Western Pomerania, Germany

C Dahms, NO Hübner, A Kossow, A Mellmann… - PloS one, 2015 - journals.plos.org
In recent years, extended-spectrum β-lactamases (ESBL) producing bacteria have been
found in livestock, mainly as asymptomatic colonizers. The zoonotic risk for people working …

Food-Borne Origins of Escherichia coli Causing Extraintestinal Infections

AR Manges, JR Johnson - Clinical infectious diseases, 2012 - academic.oup.com
Most human extraintestinal Escherichia coli infections, including those involving
antimicrobial resistant strains, are caused by the members of a limited number of distinctive …

Prevalence and Molecular Epidemiology of CTX-M Extended-Spectrum β-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae in Russian Hospitals

M Edelstein, M Pimkin, I Palagin… - Antimicrobial agents …, 2003 - Am Soc Microbiol
ABSTRACT A total of 904 consecutive nosocomial isolates of Escherichia coli and Klebsiella
pneumoniae collected from 28 Russian hospitals were screened for production of extended …

Antibiotic resistance gene abundances associated with waste discharges to the Almendares River near Havana, Cuba

DW Graham, S Olivares-Rieumont… - … science & technology, 2011 - ACS Publications
Considerable debate exists over the primary cause of increased antibiotic resistance (AR)
worldwide. Evidence suggests increasing AR results from overuse of antibiotics in medicine …

World Health Organization ranking of antimicrobials according to their importance in human medicine: a critical step for developing risk management strategies for the …

FJ Angulo, P Collignon, JH Powers… - Clinical infectious …, 2009 - academic.oup.com
The use of antimicrobials in food animals creates an important source of antimicrobial-
resistant bacteria that can spread to humans through the food supply. Improved …

Molecular analysis of blaSHV, blaTEM, and blaCTX-M in extended-spectrum β-lactamase producing Enterobacteriaceae recovered from fecal specimens of …

H Ejaz, S Younas, KOA Abosalif, K Junaid… - PLoS …, 2021 - journals.plos.org
Colonization of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae
as animal gut microbiota is a substantial global threat. This study aimed to determine the …