Homocysteine–from disease biomarker to disease prevention

AD Smith, H Refsum - Journal of internal medicine, 2021 - Wiley Online Library
We have reviewed the literature and have identified more than 100 diseases or conditions
that are associated with raised concentrations of plasma total homocysteine. The …

Systematic review of environmental risk factors for obsessive-compulsive disorder: a proposed roadmap from association to causation

G Brander, A Perez-Vigil, H Larsson… - … & Biobehavioral Reviews, 2016 - Elsevier
Objective To synthesize the current knowledge on possible environmental risk factors for
Obsessive-Compulsive Disorder (OCD). Method We conducted a systematic review …

Comparison of serum B12, folate and homocysteine concentrations in children with autism spectrum disorder or attention deficit hyperactivity disorder and healthy …

Ç Yektaş, M Alpay, AE Tufan - Neuropsychiatric disease and …, 2019 - Taylor & Francis
Objective We aimed to investigate the serum concentrations of vitamin B12, folate and
homocysteine in children diagnosed with attention deficit hyperactivity disorder (ADHD) or …

Vitamin B12, folic acid, homocysteine and vitamin D levels in children and adolescents with obsessive compulsive disorder

E Esnafoğlu, E Yaman - Psychiatry research, 2017 - Elsevier
Obsessive compulsive disorder (OCD) is a complex disorder with a poorly understood
aetiopathogenesis. One carbon metabolism that includes vitamin B12, folic acid and …

Associations between serum homocysteine levels and anxiety and depression among children and adolescents in Taiwan

KH Chung, HY Chiou, YH Chen - Scientific reports, 2017 - nature.com
Although evidence suggests that homocysteine levels are elevated in severe mental illness
in children, findings regarding homocysteine levels in youth with anxiety and depression are …

Alterations in gut vitamin and amino acid metabolism are associated with symptoms and neurodevelopment in children with autism spectrum disorder

J Zhu, X Hua, T Yang, M Guo, Q Li, L Xiao, L Li… - Journal of Autism and …, 2022 - Springer
Metabolic disturbance may be implicated in the pathogenesis of autism. This study aimed to
investigate the gut metabolomic profiles of autistic children and to analyze potential …

Genome-wide DNA methylation analysis in obsessive-compulsive disorder patients

W Yue, W Cheng, Z Liu, Y Tang, T Lu, D Zhang… - Scientific reports, 2016 - nature.com
Literatures have suggested that not only genetic but also environmental factors, interactively
accounted for susceptibility of obsessive-compulsive disorder (OCD). DNA methylation may …

Genetic and epigenetic architecture of obsessive-compulsive disorder: in search of possible diagnostic and prognostic biomarkers

F Bellia, M Vismara, E Annunzi, C Cifani… - Journal of psychiatric …, 2021 - Elsevier
Abstract Obsessive-Compulsive Disorder (OCD) is a prevalent and severe clinical condition
whose hallmarks are excessive, unwanted thoughts (obsessions) and repetitive behaviors …

Exploring the role of BDNF DNA methylation and hydroxymethylation in patients with obsessive compulsive disorder

C D'Addario, F Bellia, B Benatti, B Grancini… - Journal of Psychiatric …, 2019 - Elsevier
Obsessive-compulsive disorder (OCD) is a clinically heterogeneous neuropsychiatric
condition associated with profound disability, whose susceptibility, stemming from genetic …

Water-soluble vitamin insufficiency, deficiency and supplementation in children and adolescents with a psychiatric disorder: a systematic review and meta-analysis

N Prades, E Varela, I Flamarique… - Nutritional …, 2023 - Taylor & Francis
Nutrition is fundamental for brain development, but relatively little is known about water-
soluble vitamin (WSV) levels and the effect of supplementation on psychiatry symptoms in …