This article provides an encompassing review of the current pipeline of putative and developed treatments for tuberculosis, including multidrug-resistant strains. The review has …
A Schami, MN Islam, JT Belisle… - Frontiers in Cellular and …, 2023 - frontiersin.org
In the past few decades, drug-resistant (DR) strains of Mycobacterium tuberculosis (M. tb), the causative agent of tuberculosis (TB), have become increasingly prevalent and pose a …
The mortality incidence from nontuberculous mycobacteria (NTM) infections has been steadily developing globally. These bacterial agents were once thought to be innocent …
A Negi, S Perveen, R Gupta, PP Singh… - Journal of Medicinal …, 2024 - ACS Publications
Delamanid, bedaquiline, and pretomanid have been recently added in the anti-tuberculosis (anti-TB) treatment regimens and have emerged as potential solutions for combating drug …
T Bourguignon, JA Godinez-Leon, R Gref - Pharmaceutics, 2023 - mdpi.com
Tuberculosis (TB) is currently the second deadliest infectious disease. Existing antitubercular therapies are long, complex, and have severe side effects that result in low …
Tuberculosis (TB) is a major global health problem and the second most prevalent infectious killer after COVID-19. It is caused by Mycobacterium tuberculosis (Mtb) and has become …
The prevalence of tuberculosis (TB) remains the leading cause of death from a single infectious agent, ranking it above all other contagious diseases. The problem to tackle this …
NA Zahra, AC Vagiona, R Uddin… - International Journal of …, 2023 - mdpi.com
Tuberculosis remains the leading cause of death from a single pathogen. On the other hand, antimicrobial resistance (AMR) makes it increasingly difficult to deal with this disease. We …
Pyrazinamide (PZA) is an essential first-line tuberculosis drug for its unique mechanism of action active against multidrug-resistant-TB (MDR-TB). Thus, the aim of updated meta …