Clinical instrumentation and applications of Raman spectroscopy

I Pence, A Mahadevan-Jansen - Chemical Society Reviews, 2016 - pubs.rsc.org
Clinical diagnostic devices provide new sources of information that give insight about the
state of health which can then be used to manage patient care. These tools can be as simple …

Raman spectroscopy for cancer detection and cancer surgery guidance: translation to the clinics

IP Santos, EM Barroso, TCB Schut, PJ Caspers… - Analyst, 2017 - pubs.rsc.org
Oncological applications of Raman spectroscopy have been contemplated, pursued, and
developed at academic level for at least 25 years. Published studies aim to detect pre …

Raman technologies in cancer diagnostics

LA Austin, S Osseiran, CL Evans - Analyst, 2016 - pubs.rsc.org
Despite significant effort, cancer still remains a leading cause of death worldwide. In order to
reduce its burden, the development and improvement of noninvasive strategies for early …

Raman spectroscopy and chemometrics: A potential universal method for diagnosing cancer

NM Ralbovsky, IK Lednev - Spectrochimica Acta Part A: Molecular and …, 2019 - Elsevier
Cancer is the second-leading cause of death worldwide. It affects an unfathomable number
of people, with almost 16 million Americans currently living with it. While many cancers can …

Raman spectroscopy for rapid evaluation of surgical margins during breast cancer lumpectomy

WC Zúñiga, V Jones, SM Anderson, A Echevarria… - Scientific reports, 2019 - nature.com
Failure to precisely distinguish malignant from healthy tissue has severe implications for
breast cancer surgical outcomes. Clinical prognoses depend on precisely distinguishing …

Portable spectroscopic system for in vivo skin neoplasms diagnostics by Raman and autofluorescence analysis

YA Khristoforova, IA Bratchenko… - Journal of …, 2019 - Wiley Online Library
The present paper studies the applicability of a portable cost‐effective spectroscopic system
for the optical screening of skin tumors. in vivo studies of Raman scattering and …

The complementary value of intraoperative fluorescence imaging and Raman spectroscopy for cancer surgery: combining the incompatibles

LJ Lauwerends, H Abbasi, TC Bakker Schut… - European Journal of …, 2022 - Springer
A clear margin is an important prognostic factor for most solid tumours treated by surgery.
Intraoperative fluorescence imaging using exogenous tumour-specific fluorescent agents …

Discrimination of malignant and normal kidney tissue with short wave infrared dispersive Raman spectroscopy

M Haifler, I Pence, Y Sun, A Kutikov… - Journal of …, 2018 - Wiley Online Library
Renal mass biopsy is still controversial due to imperfect accuracy. Raman spectroscopy
(RS) demonstrated promise as an in vivo real‐time, nondestructive diagnostic tool in many …

Clinical characterization of in vivo inflammatory bowel disease with Raman spectroscopy

IJ Pence, DB Beaulieu, SN Horst, X Bi… - Biomedical Optics …, 2017 - opg.optica.org
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease
(CD), affects over 1 million Americans and 2 million Europeans, and the incidence is …

Optical spectroscopy and chemometrics in intraoperative tumor margin assessment

E Boichenko, D Kirsanov - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Spectroscopic techniques developed in analytical chemistry have become an important part
of medical and biological research. Optical spectroscopy is widely used in research devoted …