Frontiers in the treatment of glioblastoma: Past, present and emerging

TI Janjua, P Rewatkar, A Ahmed-Cox, I Saeed… - Advanced drug delivery …, 2021 - Elsevier
Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …

Heating technology for malignant tumors: A review

HP Kok, ENK Cressman, W Ceelen… - International Journal …, 2020 - Taylor & Francis
The therapeutic application of heat is very effective in cancer treatment. Both hyperthermia,
ie, heating to 39–45° C to induce sensitization to radiotherapy and chemotherapy, and …

Pangolin-inspired untethered magnetic robot for on-demand biomedical heating applications

RH Soon, Z Yin, MA Dogan, NO Dogan… - Nature …, 2023 - nature.com
Untethered magnetic miniature soft robots capable of accessing hard-to-reach regions can
enable safe, disruptive, and minimally invasive medical procedures. However, the soft body …

Bioorthogonal chemistry for prodrug activation in vivo

Q Fu, S Shen, P Sun, Z Gu, Y Bai, X Wang… - Chemical Society …, 2023 - pubs.rsc.org
Prodrugs have emerged as a major strategy for addressing clinical challenges by improving
drug pharmacokinetics, reducing toxicity, and enhancing treatment efficacy. The emergence …

Recent advancements in electroporation technologies: from bench to clinic

SN Campelo, PH Huang, CR Buie… - Annual Review of …, 2023 - annualreviews.org
Over the past decade, the increased adoption of electroporation-based technologies has led
to an expansion of clinical research initiatives. Electroporation has been utilized in …

Immunomodulation and targeted drug delivery with high intensity focused ultrasound (HIFU): Principles and mechanisms

H Ashar, A Ranjan - Pharmacology & Therapeutics, 2023 - Elsevier
High intensity focused ultrasound (HIFU) is a non-invasive and non-ionizing sonic energy-
based therapeutic technology for inducing thermal and non-thermal effects in tissues …

Ultrasound‐Sensitive Intelligent Nanosystems: A Promising Strategy for the Treatment of Neurological Diseases

X Pan, W Huang, G Nie, C Wang… - Advanced Materials, 2024 - Wiley Online Library
Neurological diseases are a major global health challenge, affecting hundreds of millions of
people worldwide. Ultrasound therapy plays an irreplaceable role in the treatment of …

Advanced near‐infrared light approaches for neuroimaging and neuromodulation

H Yin, W Jiang, Y Liu, D Zhang, F Wu, Y Zhang, C Li… - …, 2023 - Wiley Online Library
Almost all physiological processes of animals are controlled by the brain, including
language, cognitive, memory, learning, emotion and so forth. Minor brain dysfunction usually …

Principles and applications of sono-optogenetics

F Yang, SJ Kim, X Wu, H Cui, SK Hahn… - Advanced drug delivery …, 2023 - Elsevier
Optogenetics has revolutionized neuroscience research through its spatiotemporally precise
activation of specific neurons by illuminating light on opsin-expressing neurons. A long …

Magnetically actuated helical microrobot with magnetic nanoparticle retrieval and sequential dual-drug release abilities

H Lee, S Park - ACS Applied Materials & Interfaces, 2023 - ACS Publications
Cancer is one of the diseases with high mortality worldwide. Various methods for cancer
treatment are being developed, and among them, magnetically driven microrobots capable …