Cancer is a multifactorial disease characterized by various hallmarks, including uncontrolled
cell growth, evasion of apoptosis, sustained angiogenesis, tissue invasion, and metastasis …

Background With aging of the population and improvements in diagnosis, treatment, and
supportive care, the number of cancer survivors in the United States has increased; updated …

Despite significant advances in cancer therapeutics, chemotherapy remains the cornerstone
of treatment for many tumors. Importantly, however, chemotherapy-induced toxicity …

A novel and efficient cancer therapy was developed using a smart hydrogel containing
multifunctional bimetallic organic frameworks and anticancer drugs. The injectable self …

Pediatric cancers are rare diseases, and children without known germline predisposing
conditions who develop a second malignancy during developmental ages are extremely …

Abstract A series of 4-(N-dithiobenzyl piperazine)-1, 8-naphthalimide derivatives 4–6 were
designed, synthesized, and evaluated as novel multi-target antitumor agents. 3-(4, 5 …

Among the most health-influencing threats, microbial infections and cancer have attracted a
mounting interest in the medical field. To face these threats, research is directed to improve …

In this study, a series of 2-Aryl-1H-benzo [d] imidazole derivatives were developed to target
intra-and extracellular microtubule networks. Compounds O-7 and O-10 showed impressive …

Progressive neurocognitive dysfunction is the leading cause of a reduced quality of life in
patients with primary brain tumors. Understanding how the human brain responds to cancer …

Lung cancer has traditionally been associated with advanced age; however, its increasing
incidence among young adults raises concerning questions regarding its etiology and …