Bio-inks for 3D bioprinting: recent advances and future prospects

I Donderwinkel, JCM Van Hest, NR Cameron - Polymer Chemistry, 2017 - pubs.rsc.org
In the last decade, interest in the field of three-dimensional (3D) bioprinting has increased
enormously. 3D bioprinting combines the fields of developmental biology, stem cells, and …

3D bioprinting for drug discovery and development in pharmaceutics

W Peng, P Datta, B Ayan, V Ozbolat, D Sosnoski… - Acta biomaterialia, 2017 - Elsevier
Successful launch of a commercial drug requires significant investment of time and financial
resources wherein late-stage failures become a reason for catastrophic failures in drug …

[HTML][HTML] Microfluidic-enhanced 3D bioprinting of aligned myoblast-laden hydrogels leads to functionally organized myofibers in vitro and in vivo

M Costantini, S Testa, P Mozetic, A Barbetta, C Fuoco… - Biomaterials, 2017 - Elsevier
We present a new strategy for the fabrication of artificial skeletal muscle tissue with
functional morphologies based on an innovative 3D bioprinting approach. The methodology …

Bioprinting towards physiologically relevant tissue models for pharmaceutics

W Peng, D Unutmaz, IT Ozbolat - Trends in biotechnology, 2016 - cell.com
Improving the ability to predict the efficacy and toxicity of drug candidates earlier in the drug
discovery process will speed up the introduction of new drugs into clinics. 3D in vitro …

[HTML][HTML] Recent development in multizonal scaffolds for osteochondral regeneration

L Yu, S Cavelier, B Hannon, M Wei - Bioactive Materials, 2023 - Elsevier
Osteochondral (OC) repair is an extremely challenging topic due to the complex biphasic
structure and poor intrinsic regenerative capability of natural osteochondral tissue. In …

[HTML][HTML] Recent progress in cartilage tissue engineering—our experience and future directions

Y Liu, G Zhou, Y Cao - Engineering, 2017 - Elsevier
Given the limited spontaneous repair that follows cartilage injury, demand is growing for
tissue engineering approaches for cartilage regeneration. There are two major applications …

Biomaterial-based scaffolds–current status and future directions

T Garg, AK Goyal - Expert opinion on drug delivery, 2014 - Taylor & Francis
Introduction: Biomaterial-based scaffold formulations (three-dimensional Porous matrix,
nano-fibre mesh, hydrogels and microspheres) are the major components that are used to …

[HTML][HTML] The impact of microfluidics in high-throughput drug-screening applications

P De Stefano, E Bianchi, G Dubini - Biomicrofluidics, 2022 - pubs.aip.org
Drug discovery is an expensive and lengthy process. Among the different phases, drug
discovery and preclinical trials play an important role as only 5–10 of all drugs that begin …

[HTML][HTML] Multifaceted signaling regulators of chondrogenesis: Implications in cartilage regeneration and tissue engineering

JD Green, V Tollemar, M Dougherty, Z Yan, L Yin, J Ye… - Genes & diseases, 2015 - Elsevier
Defects of articular cartilage present a unique clinical challenge due to its poor self-healing
capacity and avascular nature. Current surgical treatment options do not ensure consistent …

Myoblast 3D bioprinting to burst in vitro skeletal muscle differentiation

FL Ronzoni, F Aliberti, F Scocozza… - Journal of Tissue …, 2022 - Wiley Online Library
Skeletal muscle regeneration is one of the major areas of interest in sport medicine as well
as trauma centers. Three‐dimensional (3D) bioprinting (BioP) is nowadays widely adopted …