Assessing developability early in the discovery process for novel biologics
Beyond potency, a good developability profile is a key attribute of a biological drug.
Selecting and screening for such attributes early in the drug development process can save …
Selecting and screening for such attributes early in the drug development process can save …
Structure of thaumatin under acidic conditions: Structural insight into the conformations in lysine residues responsible for maintaining the sweetness after heat …
T Masuda, K Okubo, S Baba, M Suzuki, F Tani… - Food Chemistry, 2022 - Elsevier
Thaumatin is an intensely sweet-tasting protein. Its sweetness persists when heated under
acidic conditions, but disappears when heated at a pH above 7.0. To clarify how the …
acidic conditions, but disappears when heated at a pH above 7.0. To clarify how the …