Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system that
causes significant disability and healthcare burden. The treatment of MS has evolved over …

The NLRP3 inflammasome is an intracellular multiprotein complex that plays an essential
role in the innate immune system by identifying and eliminating a plethora of endogenous …

Importance With few approved multiple sclerosis therapies in the pediatric population, there
is a need for further approved treatment options. Limited data exist for dimethyl fumarate …

Multiple sclerosis treatment made substantial headway during the last two decades with the
implementation of therapeutics with new modes of action and routes of application. We are …

Neurodegenerative diseases have been a weighty problem in elder people who might be
stricken with motor or/and cognition defects with lower life quality urging for effective …

Dimethyl fumarate (DMF) is a widely used oral disease-modifying therapy for multiple
sclerosis (MS). Its efficacy and safety profiles are supported by over a decade of experience …

Background and objectives Dimethyl fumarate (DMF), an oral disease-modifying therapy
with an established benefit and well-described safety profile, is among the most commonly …

Background: Dimethyl fumarate (DMF) depletes CD8+ and CD4+ T cells, and cases of
herpes zoster (HZ) in patients with multiple sclerosis (MS) on DMF have been documented …

Traumatic brain injury (TBI) is a major global health problem that affects both civilian and
military populations worldwide. Post-injury acute, sub-acute, and chronic progression of …

Multiple sclerosis (MS) is a chronic inflammatory, demyelinating and neurodegenerative
disorder of the central nervous system. Disease-modifying drugs (DMDs) and subsequent …