Impact of sex and gender on COVID-19 outcomes in Europe

C Gebhard, V Regitz-Zagrosek, HK Neuhauser… - Biology of sex …, 2020 - Springer
Abstract Background Emerging evidence from China suggests that coronavirus disease
2019 (COVID-19) is deadlier for infected men than women with a 2.8% fatality rate being …

Considering how biological sex impacts immune responses and COVID-19 outcomes

EP Scully, J Haverfield, RL Ursin… - Nature Reviews …, 2020 - nature.com
A male bias in mortality has emerged in the COVID-19 pandemic, which is consistent with
the pathogenesis of other viral infections. Biological sex differences may manifest …

Higher mortality of COVID-19 in males: sex differences in immune response and cardiovascular comorbidities

LA Bienvenu, J Noonan, X Wang… - Cardiovascular …, 2020 - academic.oup.com
The high mortality rate of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
infection is a critical concern of the coronavirus disease 2019 (COVID-19) pandemic …

Sex differences in immunity to viral infections

H Jacobsen, SL Klein - Frontiers in immunology, 2021 - frontiersin.org
The ongoing COVID-19 pandemic has increased awareness about sex-specific differences
in immunity and outcomes following SARS-CoV-2 infection. Strong evidence of a male bias …

Sex hormone signaling and regulation of immune function

JP Hoffmann, JA Liu, K Seddu, SL Klein - Immunity, 2023 - cell.com
Immune responses to antigens, including innocuous, self, tumor, microbial, and vaccine
antigens, differ between males and females. The quest to uncover the mechanisms for …

Sex differences in immunity

NM Wilkinson, HC Chen, MG Lechner… - Annual review of …, 2022 - annualreviews.org
Strong epidemiological evidence now exists that sex is an important biologic variable in
immunity. Recent studies, for example, have revealed that sex differences are associated …

Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts

MP Stewart, R Langer, KF Jensen - Chemical reviews, 2018 - ACS Publications
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Plasmacytoid dendritic cells: development, regulation, and function

B Reizis - Immunity, 2019 - cell.com
Plasmacytoid dendritic cells (pDCs) are a unique sentinel cell type that can detect pathogen-
derived nucleic acids and respond with rapid and massive production of type I interferon …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Sexual dimorphism in innate immunity

S Jaillon, K Berthenet, C Garlanda - Clinical reviews in allergy & …, 2019 - Springer
Sexual dimorphisms account for differences in clinical manifestations or incidence of
infectious or autoimmune diseases and malignancy between females and males. Females …