The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Prenatal substance use is a critical public health concern that is linked with several harmful
maternal and fetal consequences. The most frequently used substance in pregnancy is …

Compulsive drug seeking that is associated with addiction is hypothesized to follow a
heuristic framework that involves three stages (binge/intoxication, withdrawal/negative affect …

Oxytocin, a hypothalamic nonapeptide, is linked to increased levels of social interaction, well-
being and anti-stress effects. The effects of oxytocin that is released by sensory stimulation …

Stress is commonly regarded as an important trigger for relapse and a significant factor that
promotes increased motivation to drink in some individuals. However, the relationship …

The neuropeptide oxytocin (OT) regulates rodent, primate and human social behaviors and
stress responses. OT binding studies employing 125 Id (CH 2) 5-[Tyr (Me) 2, Thr 4, Tyr-NH 2 …

Abstract Nose-to-brain (N-to-B) delivery offers to protein and peptide drugs the possibility to
reach the brain in a non-invasive way. This article is a comprehensive review of the state-of …

Current concepts of human sociality highlight a fundamental role of the hypothalamic
peptide oxytocin (OXT) in the formation and maintenance of social relationships. However …

Psychiatry and Psychosomatic Medicine are concerned with medical conditions affecting
brain, mind and behaviour in manifold ways. Traditional approaches have focused on a …

Substance use disorders (SUD) and posttraumatic stress disorder (PTSD) are chronic,
debilitating conditions that frequently co-occur. Individuals with co-occurring SUD and PTSD …