This review article provides an historical perspective on some of the major research
advances of relevance to ruminant livestock gastrointestinal nematode control over the last …

Immunology was founded by studying the body's response to infectious microorganisms,
and yet microbial prokaryotes only tell half the story of the immune system. Eukaryotic …

Most phytoparasitic nematodes infect plant roots and some species have evolved
sophisticated interactive relationships with host cells to sustain a sedentary parasitic habit …

Plant parasitic nematodes have been, so far, refractory to transformation or mutagenesis.
The functional analysis of nematode genes relies on the development of reverse genetic …

Substantial progress has been made in the last decade in identifying several antigens from
Haemonchus contortus which, in their native form, stimulate useful levels of protective …

Background Plant parasitic nematodes are major pathogens of most crops. Molecular
characterization of these species as well as the development of new techniques for control …

Direct assessments of gene function in parasitic flatworms have been hampered by the lack
of effective tools to alter gene expression. The aim of the present study was to use RNA …

Recent transcriptome and genome projects have dramatically expanded the biological data
available across the phylum Nematoda. Here we summarize analyses of these sequences …

In this paper, we used the genetic manipulation technique known as RNA-interference to
suppress the expression of a target, cathepsin B, gene in the platyhelminth parasite …

RNA interference (RNAi) has become an invaluable tool for the functional analysis of genes
in a wide variety of organisms including the free-living nematode Caenorhabditis elegans …