A bird's eye view is now demanded in the area of cancer research to suppress the suffering
of cancer patient and mediate the lack of treatment related to chemotherapy. Chemotherapy …

The major function of the respiratory epithelium was once thought to be that of a physical
barrier. However, it constitutes the interface between the internal milieu and the external …

The agent of Q fever, Coxiella burnetii, is an obligate intracellular bacterium that causes
acute and chronic infections. The study of C. burnetii pathogenesis has benefited from two …

The αVβ3 integrin is implicated in human tumor metastasis and in angiogenesis. The design
of low-molecular-mass αVβ3 antagonists by “spatial screening” led to the highly active …

Intra-abdominal adhesion formation and reformation after surgery is a cause of significant
morbidity, resulting in infertility and pain. The understanding of the pathogenesis of …

Cell–cell and cell–matrix interactions play a major role in biology. An important class of
surface receptors are the integrins, which exist in a number of subtypes and are involved in …

Field isolates of foot-and-mouth disease virus (FMDV) have been shown to use the RGD-
dependent integrin αvβ3 as a cellular receptor on cultured cells. However, several other …

Integrins are cell adhesion receptors that mediate cell-extracellular matrix and cell-cell
interactions. Each integrin consists of two glycoprotein subunits (alpha and beta). We have …

This review will discuss a number of specific cell adhesion molecules present on the surface
of endothelial and epithelial cells in the lung. Molecules such as integrins, proteoglycans …

Field strains of Foot-and-mouth disease virus (FMDV) use a number of α v-integrins as
receptors to initiate infection on cultured cells, and integrins are believed to be the receptors …