Clinical utility of mesenchymal stem/stromal cells in regenerative medicine and cellular therapy

VV Maldonado, NH Patel, EE Smith, CL Barnes… - Journal of biological …, 2023 - Springer
Mesenchymal stem/stromal cells (MSCs) have been carefully examined to have tremendous
potential in regenerative medicine. With their immunomodulatory and regenerative …

Extracellular vesicles as therapeutics for brain injury and disease

D Upadhya, AK Shetty - Current Pharmaceutical Design, 2019 - ingentaconnect.com
Extracellular vesicles (EVs) are gaining tremendous importance in comprehending central
nervous system (CNS) function and treating neurological disorders because of their role in …

[HTML][HTML] Long noncoding RNA NKILA transferred by astrocyte-derived extracellular vesicles protects against neuronal injury by upregulating NLRX1 through binding to …

B He, W Chen, J Zeng, W Tong, P Zheng - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
The study aims to investigate the effects of long noncoding RNA (lncRNA) transmitted
nuclear factor-κB interacting lncRNA (NKILA)-containing astrocyte-derived small …

Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats

P Izquierdo-Altarejos, A Cabrera-Pastor… - Journal of …, 2023 - Springer
Chronic hyperammonemia, a main contributor to hepatic encephalopathy (HE), leads to
neuroinflammation which alters neurotransmission leading to cognitive impairment. There …

[HTML][HTML] The challenges of the bioactive scaffolds in nervous system: from their molecular conformation to their therapeutic efficiency

R Ramos-Zúñiga, I Segura-Duran… - Neurology …, 2022 - Elsevier
Introduction Biomaterials are currently used in a wide range of applications in regenerative
medicine, and to date, a large number of compounds have been designed as approach to …

Neuroprotective Effects of Nanowired Delivery of Cerebrolysin with Mesenchymal Stem Cells and Monoclonal Antibodies to Neuronal Nitric Oxide Synthase in Brain …

HS Sharma, DF Muresanu, A Nozari… - … in Nanomedicine in …, 2023 - Springer
Concussive head injury (CHI) is one of the major risk factors in developing Alzheimer's
disease (AD) in military personnel at later stages of life. Breakdown of the blood–brain …

A promising strategy for non-arteritic anterior ischemic optic neuropathy: intravitreal mesenchymal stem cell exosome

D Li, Y Gong - Current Stem Cell Research & Therapy, 2021 - ingentaconnect.com
Non-arteritic anterior ischemic optic neuropathy (NAION) is a leading cause of optic
nerverelated permanent visual impairment among individuals of over 50 years of age after …