Single muscle fibre contractile function with ageing

GJ Grosicki, CS Zepeda… - The Journal of …, 2022 - Wiley Online Library
Ageing is accompanied by decrements in the size and function of skeletal muscle that
compromise independence and quality of life in older adults. Developing therapeutic …

Contractile force assessment methods for in vitro skeletal muscle tissues

C Vesga-Castro, J Aldazabal, A Vallejo-Illarramendi… - Elife, 2022 - elifesciences.org
Over the last few years, there has been growing interest in measuring the contractile force
(CF) of engineered muscle tissues to evaluate their functionality. However, there are still no …

Automatic and unbiased segmentation and quantification of myofibers in skeletal muscle

A Waisman, AM Norris, M Elías Costa, D Kopinke - Scientific reports, 2021 - nature.com
Skeletal muscle has the remarkable ability to regenerate. However, with age and disease
muscle strength and function decline. Myofiber size, which is affected by injury and disease …

Effects of training, detraining, and retraining on strength, hypertrophy, and myonuclear number in human skeletal muscle

N Psilander, E Eftestøl, KT Cumming… - Journal of applied …, 2019 - journals.physiology.org
Previously trained mouse muscles acquire strength and volume faster than naïve muscles; it
has been suggested that this is related to increased myonuclear density. The present study …

Effects of elevated H+ and Pi on the contractile mechanics of skeletal muscle fibres from young and old men: implications for muscle fatigue in humans

CW Sundberg, SK Hunter, SW Trappe… - The Journal of …, 2018 - Wiley Online Library
Key points The mechanisms responsible for the loss in muscle power and increased
fatigability with ageing are unresolved. We show that the contractile mechanics of fibres from …

Myosoft: An automated muscle histology analysis tool using machine learning algorithm utilizing FIJI/ImageJ software

L Encarnacion-Rivera, S Foltz, HC Hartzell, H Choo - PloS one, 2020 - journals.plos.org
Skeletal muscle is comprised of a heterogeneous population of muscle fibers which can be
classified by their metabolic and contractile properties (fiber “types”). Fiber type is a primary …

Improvements in skeletal muscle fiber size with resistance training are age-dependent in older adults: a systematic review and meta-analysis

CR Straight, MV Fedewa, MJ Toth… - Journal of Applied …, 2020 - journals.physiology.org
As studies examining the hypertrophic effects of resistance training (RT) at the cellular level
have produced inconsistent results, we performed a systematic review and meta-analysis to …

[HTML][HTML] Sex-and fiber-type-related contractile properties in human single muscle fiber

Y Jeon, J Choi, HJ Kim, H Lee, JY Lim… - Journal of Exercise …, 2019 - ncbi.nlm.nih.gov
This study aimed to examine the distribution and contractile properties of single muscle fiber
sex/myosin heavy chain (MHC) type-related differences and to evaluate the correlation of …

[HTML][HTML] The aging athlete: paradigm of healthy aging

KJ Gries, SW Trappe - International journal of sports medicine, 2022 - thieme-connect.com
The Exercise Boom of the 1970's resulted in the adoption of habitual exercise in a significant
portion of the population. Many of these individuals are defying the cultural norms by …

The Human Muscle Size and Strength Relationship. Effects of Architecture, Muscle Force and Measurement Location.

TG Balshaw, T Maden-Wilkinson… - Medicine & Science …, 2021 - shura.shu.ac.uk
Purpose This study aimed to determine the best muscle size index of muscle strength by
establishing if incorporating muscle architecture measurements improved the human muscle …