Cellular signaling networks are the foundation which determines the fate and function of
cells as they respond to various cues and stimuli. The discovery of fluorescent proteins over …

Ca2+ regulation of contraction in vertebrate striated muscle is exerted primarily through
effects on the thin filament, which regulate strong cross-bridge binding to actin. Structural …

Abstract FATCAT 2.0 server (http://fatcat. godziklab. org/), provides access to a flexible
protein structure alignment algorithm developed in our group. In such an alignment …

The quality of genetically encoded calcium indicators (GECIs) has improved dramatically in
recent years, but high-performing ratiometric indicators are still rare. Here we describe a …

Troponin complex is a component of skeletal and cardiac muscle thin filaments. It consists of
three subunits—troponin I, T, and C, and it plays a crucial role in muscle activity, connecting …

Troponin is essential in Ca2+ regulation of skeletal and cardiac muscle contraction. It
consists of three subunits (TnT, TnC and TnI) and, together with tropomyosin, is located on …

Suspected acute myocardial infarction (AMI) is one of the leading causes of admission to the
emergency departments in Western countries but also an increasing cause in many other …

The review focuses on the unique spectral features of pyrene that can be utilized to
investigate protein structure and conformation. Pyrene is a fluorescent probe that can be …

Background Central to protein biology is the understanding of how structural elements give
rise to observed function. The surfeit of protein structural data enables development of …

Scallops: Biology, Ecology, Aquaculture and Fisheries, Third Edition, continues its history as
the definitive resource on scallops, covering all facets of scallop biology, including anatomy …