Abstract Pre-, post-, and remote conditioning of the myocardium are well described adaptive
responses that markedly enhance the ability of the heart to withstand a prolonged …

Thgoal of this study was to evaluate the efficacy of the antioxidant olive constituent,
oleuropein, on infarct size, oxidative damage, and the metabolic profile in rabbits subjected …

Cholesterol homeostasis is a highly regulated process in human body because of its several
functions underlying the biology of cell membranes, the synthesis of all steroid hormones …

Objective: We investigated the influence of experimental hyperlipidemia on the formation of
cardiac NO, superoxide, and peroxynitrite (ONOO−) in rat hearts. Methods: Wistar rats were …

It is clear that multiple signalling pathways regulate the critical balance between cell death
and survival in myocardial ischaemia–reperfusion. Recent attention has focused on the …

Following a period of ischemia (local restriction of blood supply to a tissue), the restoration of
blood supply to the affected area causes significant tissue damage. This is known as …

Brief transient episodes of nonlethal myocardial ischemia protect or “precondition” the heart
and render the myocardium resistant to a subsequent more sustained ischemic insult. The …

Hyperlipidaemia is a well‐established risk factor for cardiovascular diseases and therefore,
many animal model have been developed to mimic the human abnormal elevation of blood …

One or several short cycles of ischemia/reperfusion before (preconditioning) or after
(postconditioning) a sustained coronary occlusion with subsequent reperfusion reduce the …

Hypercholesterolaemia is considered to be a principle risk factor for cardiovascular disease,
having direct negative effects on the myocardium itself, in addition to the development of …